First report of chemical composition and cytotoxicity evaluation of Foraminispora rugosa basidiomata from Brazil
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2022Autor
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Abstract
Foraminispora rugosa is a species reported from Brazil, Venezuela, French Guiana, Costa Rica and Cuba. It is a basidiomycete in the Ganodermataceae family. In this study, both chemical composition and cytotoxicity of the ethanolic extract of F. rugosa were investigated for the frst time. Results: Phylogenetic analysis confrmed the identifcation of the specimens, and the results of cytotoxicity assays showed that at concentrations of 7.8–500.0 µg/mL the ethanolic extract displayed weak cytotoxic ...
Foraminispora rugosa is a species reported from Brazil, Venezuela, French Guiana, Costa Rica and Cuba. It is a basidiomycete in the Ganodermataceae family. In this study, both chemical composition and cytotoxicity of the ethanolic extract of F. rugosa were investigated for the frst time. Results: Phylogenetic analysis confrmed the identifcation of the specimens, and the results of cytotoxicity assays showed that at concentrations of 7.8–500.0 µg/mL the ethanolic extract displayed weak cytotoxicity against the tested cell lines. Five oxylipins were identifed by ultra high performance liquid chromatography coupled with quad- rupole time-of-fight and mass spectrometry (UHPLC-QTOF–MS). Conclusions: This study provides new insights into the current knowledge of bioactive compounds produced by macrofungi, and provides data for future biological assays with relative selectivity and safety. ...
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Botanical studies. Germany. Vol. 63 (Nov. 2022), e33, 9 p.
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Estrangeiro
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Artigos de Periódicos (39541)Ciências Exatas e da Terra (6036)
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Artigos de Periódicos (39541)Ciências da Saúde (10601)
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Artigos de Periódicos (39541)Ciências Biológicas (3081)
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