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dc.contributor.authorGarcia, Viviane de Oliveirapt_BR
dc.contributor.authorFronza, Marciopt_BR
dc.contributor.authorVon Borowski, Rafael Gomespt_BR
dc.contributor.authorSilva, Genivaldo Alvespt_BR
dc.contributor.authorZimmer, Aline Rigonpt_BR
dc.contributor.authorRuaro, Thais Carinept_BR
dc.contributor.authorGnoatto, Simone Cristina Baggiopt_BR
dc.contributor.authorDallegrave, Alexsandropt_BR
dc.contributor.authorSilveira, Rosa Mara Borges dapt_BR
dc.date.accessioned2024-04-12T06:20:05Zpt_BR
dc.date.issued2022pt_BR
dc.identifier.issn1999-3110pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/274675pt_BR
dc.description.abstractForaminispora rugosa is a species reported from Brazil, Venezuela, French Guiana, Costa Rica and Cuba. It is a basidiomycete in the Ganodermataceae family. In this study, both chemical composition and cytotoxicity of the ethanolic extract of F. rugosa were investigated for the frst time. Results: Phylogenetic analysis confrmed the identifcation of the specimens, and the results of cytotoxicity assays showed that at concentrations of 7.8–500.0 µg/mL the ethanolic extract displayed weak cytotoxicity against the tested cell lines. Five oxylipins were identifed by ultra high performance liquid chromatography coupled with quad- rupole time-of-fight and mass spectrometry (UHPLC-QTOF–MS). Conclusions: This study provides new insights into the current knowledge of bioactive compounds produced by macrofungi, and provides data for future biological assays with relative selectivity and safety.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofBotanical studies. Germany. Vol. 63 (Nov. 2022), e33, 9 p.pt_BR
dc.rightsOpen Accessen
dc.subjectCitotoxicidadept_BR
dc.subjectForaminispora rugosaen
dc.subjectFungospt_BR
dc.subjectGanodermataceaeen
dc.subjectOxylipinsen
dc.subjectTerpenoidsen
dc.subjectTandem mass spectraen
dc.titleFirst report of chemical composition and cytotoxicity evaluation of Foraminispora rugosa basidiomata from Brazilpt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001187128pt_BR
dc.type.originEstrangeiropt_BR


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