First report of chemical composition and cytotoxicity evaluation of Foraminispora rugosa basidiomata from Brazil
Fecha
2022Autor
Materia
Abstract
Foraminispora rugosa is a species reported from Brazil, Venezuela, French Guiana, Costa Rica and Cuba. It is a basidiomycete in the Ganodermataceae family. In this study, both chemical composition and cytotoxicity of the ethanolic extract of F. rugosa were investigated for the frst time. Results: Phylogenetic analysis confrmed the identifcation of the specimens, and the results of cytotoxicity assays showed that at concentrations of 7.8–500.0 µg/mL the ethanolic extract displayed weak cytotoxic ...
Foraminispora rugosa is a species reported from Brazil, Venezuela, French Guiana, Costa Rica and Cuba. It is a basidiomycete in the Ganodermataceae family. In this study, both chemical composition and cytotoxicity of the ethanolic extract of F. rugosa were investigated for the frst time. Results: Phylogenetic analysis confrmed the identifcation of the specimens, and the results of cytotoxicity assays showed that at concentrations of 7.8–500.0 µg/mL the ethanolic extract displayed weak cytotoxicity against the tested cell lines. Five oxylipins were identifed by ultra high performance liquid chromatography coupled with quad- rupole time-of-fight and mass spectrometry (UHPLC-QTOF–MS). Conclusions: This study provides new insights into the current knowledge of bioactive compounds produced by macrofungi, and provides data for future biological assays with relative selectivity and safety. ...
En
Botanical studies. Germany. Vol. 63 (Nov. 2022), e33, 9 p.
Origen
Estranjero
Colecciones
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Artículos de Periódicos (39166)Ciencias Exactas y Naturales (5964)
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Artículos de Periódicos (39166)Ciencias de la Salud (10550)
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Artículos de Periódicos (39166)Ciencias Biologicas (3025)
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