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First report of chemical composition and cytotoxicity evaluation of Foraminispora rugosa basidiomata from Brazil
dc.contributor.author | Garcia, Viviane de Oliveira | pt_BR |
dc.contributor.author | Fronza, Marcio | pt_BR |
dc.contributor.author | Von Borowski, Rafael Gomes | pt_BR |
dc.contributor.author | Silva, Genivaldo Alves | pt_BR |
dc.contributor.author | Zimmer, Aline Rigon | pt_BR |
dc.contributor.author | Ruaro, Thais Carine | pt_BR |
dc.contributor.author | Gnoatto, Simone Cristina Baggio | pt_BR |
dc.contributor.author | Dallegrave, Alexsandro | pt_BR |
dc.contributor.author | Silveira, Rosa Mara Borges da | pt_BR |
dc.date.accessioned | 2024-04-12T06:20:05Z | pt_BR |
dc.date.issued | 2022 | pt_BR |
dc.identifier.issn | 1999-3110 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/274675 | pt_BR |
dc.description.abstract | Foraminispora rugosa is a species reported from Brazil, Venezuela, French Guiana, Costa Rica and Cuba. It is a basidiomycete in the Ganodermataceae family. In this study, both chemical composition and cytotoxicity of the ethanolic extract of F. rugosa were investigated for the frst time. Results: Phylogenetic analysis confrmed the identifcation of the specimens, and the results of cytotoxicity assays showed that at concentrations of 7.8–500.0 µg/mL the ethanolic extract displayed weak cytotoxicity against the tested cell lines. Five oxylipins were identifed by ultra high performance liquid chromatography coupled with quad- rupole time-of-fight and mass spectrometry (UHPLC-QTOF–MS). Conclusions: This study provides new insights into the current knowledge of bioactive compounds produced by macrofungi, and provides data for future biological assays with relative selectivity and safety. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Botanical studies. Germany. Vol. 63 (Nov. 2022), e33, 9 p. | pt_BR |
dc.rights | Open Access | en |
dc.subject | Citotoxicidade | pt_BR |
dc.subject | Foraminispora rugosa | en |
dc.subject | Fungos | pt_BR |
dc.subject | Ganodermataceae | en |
dc.subject | Oxylipins | en |
dc.subject | Terpenoids | en |
dc.subject | Tandem mass spectra | en |
dc.title | First report of chemical composition and cytotoxicity evaluation of Foraminispora rugosa basidiomata from Brazil | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 001187128 | pt_BR |
dc.type.origin | Estrangeiro | pt_BR |
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