Mostrar registro simples

Blood transfusion-related immunomodulation

dc.contributor.authorVargas, Luciana do Nascimentopt_BR
dc.contributor.authorGarcia, Lais Oliveirapt_BR
dc.contributor.authorGalvão, Ananda Cristine Santospt_BR
dc.contributor.authorOnsten, Tor Gunnar Hugopt_BR
dc.contributor.authorCoitinho, Adriana Simonpt_BR
dc.contributor.authorSekine, Leopt_BR
dc.date.accessioned2017-05-24T02:26:26Zpt_BR
dc.date.issued2014pt_BR
dc.identifier.issn2357-9730pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/158440pt_BR
dc.description.abstractThe phenomenon of transfusion-related immunomodulation (TRIM) has been studied since the observation of a higher kidney allograft survival in patients who had received a higher number of transfusions. Conversely, it has been suggested as one of the possible causes related to the development of infections in patients with multiple blood transfusions and/or after a major surgery, and has been also associated with a decreased function of natural killer cells (NK) and antigen-presenting cells (APCs), reduced cell-mediated immunity, and increased regulatory T cells (Tregs). This review aimed to conceptualize TRIM and discuss some aspects related to its mechanisms and the prevention of immunomodulatory events.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoporpt_BR
dc.relation.ispartofClinical and biomedical research. Vol. 34, no. 4 (2014), p. 333-341pt_BR
dc.rightsOpen Accessen
dc.subjectImmunomodulationen
dc.subjectImunomodulacaopt_BR
dc.subjectTransfusão de sanguept_BR
dc.subjectBoold transfusionen
dc.subjectImmunisuppressionen
dc.subjectImunossupressãopt_BR
dc.subjectInfecçõespt_BR
dc.subjectInfectionen
dc.subjectLeucócitospt_BR
dc.subjectLeukocytesen
dc.titleBlood transfusion-related immunomodulationpt_BR
dc.title.alternativeImunomodulação relacionada à transfusão de hemocomponentes pt
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000954948pt_BR
dc.type.originNacionalpt_BR


Thumbnail
Nome:
000954948.pdf
Tamanho:
1.276Mb
Formato:
PDF
Descrição:
Texto completo (inglês)
Visualizar/abrir
   

Este item está licenciado na Creative Commons License

Mostrar registro simples