(TTTA)n polymorphism of CYP19 (aromatase gene) in Euro-and Afro-Brazilians

dc.contributor.author	Kvitko, Katia	pt_BR
dc.contributor.author	Nunes, Janice C. B.	pt_BR
dc.contributor.author	Hutz, Mara Helena	pt_BR
dc.date.accessioned	2010-06-05T04:17:23Z	pt_BR
dc.date.issued	2004	pt_BR
dc.identifier.issn	1415-4757	pt_BR
dc.identifier.uri	http://hdl.handle.net/10183/23378	pt_BR
dc.description.abstract	We investigated the polymorphic tetranucleotide repeat (TTTA)n located in the fourth intron of the CYP19 gene in two Brazilian populations. The frequencies of the five common alleles (A) in Euro- and Afro-Brazilians were, respectively: seven repeats (A5), 0.586 and 0.80; eight repeats (A4), 0.092 and 0.06; nine repeats (A3), 0.014 and 0.01; eleven repeats (A2), 0.284 and 0.09; twelve repeats (A1), 0.021 and 0.04. In addition, one Euro-Brazilian individual had a rare allele with 13 repeats. The allelic frequencies in Euro- and Afro-Brazilians differed statistically (p < 10-3).The two samples were found to be in Hardy-Weinberg equilibrium (p = 0,828 and p = 0,995).	en
dc.format.mimetype	application/pdf
dc.language.iso	eng	pt_BR
dc.relation.ispartof	Genetics and molecular biology. Ribeirão Preto. Vol. 27, no. 3 (Sept. 2004), p. 335-336	pt_BR
dc.rights	Open Access	en
dc.subject	CYP19	en
dc.subject	Genética	pt_BR
dc.subject	Polimorfismo	pt_BR
dc.subject	Gene polymorphism	en
dc.title	(TTTA)n polymorphism of CYP19 (aromatase gene) in Euro-and Afro-Brazilians	pt_BR
dc.type	Artigo de periódico	pt_BR
dc.identifier.nrb	000474689	pt_BR
dc.type.origin	Nacional	pt_BR

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