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dc.contributor.authorKvitko, Katiapt_BR
dc.contributor.authorNunes, Janice C. B.pt_BR
dc.contributor.authorHutz, Mara Helenapt_BR
dc.date.accessioned2010-06-05T04:17:23Zpt_BR
dc.date.issued2004pt_BR
dc.identifier.issn1415-4757pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/23378pt_BR
dc.description.abstractWe investigated the polymorphic tetranucleotide repeat (TTTA)n located in the fourth intron of the CYP19 gene in two Brazilian populations. The frequencies of the five common alleles (A) in Euro- and Afro-Brazilians were, respectively: seven repeats (A5), 0.586 and 0.80; eight repeats (A4), 0.092 and 0.06; nine repeats (A3), 0.014 and 0.01; eleven repeats (A2), 0.284 and 0.09; twelve repeats (A1), 0.021 and 0.04. In addition, one Euro-Brazilian individual had a rare allele with 13 repeats. The allelic frequencies in Euro- and Afro-Brazilians differed statistically (p < 10-3).The two samples were found to be in Hardy-Weinberg equilibrium (p = 0,828 and p = 0,995).en
dc.format.mimetypeapplication/pdf
dc.language.isoengpt_BR
dc.relation.ispartofGenetics and molecular biology. Ribeirão Preto. Vol. 27, no. 3 (Sept. 2004), p. 335-336pt_BR
dc.rightsOpen Accessen
dc.subjectCYP19en
dc.subjectGenéticapt_BR
dc.subjectPolimorfismopt_BR
dc.subjectGene polymorphismen
dc.title(TTTA)n polymorphism of CYP19 (aromatase gene) in Euro-and Afro-Brazilianspt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000474689pt_BR
dc.type.originNacionalpt_BR


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