Mostrar el registro sencillo del ítem
Clozapine use decreases the number of hospitalizations per year in patients with treatment-resistant schizophrenia
dc.contributor.author | Londero, Marina Dalla Barba | pt_BR |
dc.contributor.author | Sousa, Mathias Hasse de | pt_BR |
dc.contributor.author | Perin, Carolina Petry | pt_BR |
dc.contributor.author | Czepielewski, Letícia Sanguinetti | pt_BR |
dc.contributor.author | Claudino, Felipe Cesar de Almeida | pt_BR |
dc.contributor.author | Gama, Clarissa Severino | pt_BR |
dc.date.accessioned | 2021-11-19T04:46:34Z | pt_BR |
dc.date.issued | 2021 | pt_BR |
dc.identifier.issn | 2357-9730 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/232031 | pt_BR |
dc.description.abstract | For years, the management of schizophrenia has represented a challenge for clinicians, with antipsychotic treatments usually resulting in relapses and new hospitalizations. Clozapine has been shown to be an effective medication for treatment-resistant schizophrenia (TRS), but is currently underused due to its potential side effects. Nevertheless, research has suggested that clozapine reduces future hospitalizations in patients with TRS. This study aims to verify the rates of hospitalizations in patients with TRS under long-term use of clozapine. We retrospectively analyzed clinical data from 52 individuals with TRS before and after the use of clozapine. The mean duration of treatment with and without clozapine was 6.6 (± 3.9) and 8.5 years (± 6.6), respectively. Patients had a median of 0.5 (0.74) hospitalizations per year before the use of clozapine and 0 (0.74) hospitalizations after it (p = 0.001). Therefore, the use of clozapine resulted in an expected reduction in the number of hospitalizations per year in individuals with TRS. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Clinical and biomedical research. Porto Alegre. Vol. 41, n. 2 (2021), p. 167-169 | pt_BR |
dc.rights | Open Access | en |
dc.subject | Schizophrenia | en |
dc.subject | Esquizofrenia | pt_BR |
dc.subject | Treatment-resistant | en |
dc.subject | Hospitalização psiquiatrica | pt_BR |
dc.subject | Clozapine | en |
dc.subject | Clozapina | pt_BR |
dc.subject | Hospitalization | en |
dc.title | Clozapine use decreases the number of hospitalizations per year in patients with treatment-resistant schizophrenia | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 001132484 | pt_BR |
dc.type.origin | Nacional | pt_BR |
Ficheros en el ítem
Este ítem está licenciado en la Creative Commons License
![](/themes/Mirage2Novo//images/lume/cc.png)
-
Artículos de Periódicos (39351)Ciencias Humanas (6733)