Navegação Ciências Biológicas por Título
Resultados 2913-2932 de 3042
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TrkB-targeted therapy for mucoepidermoid carcinoma
(2020) [Artigo de periódico]The brain-derived neurotrophic factor (BDNF)/tyrosine receptor kinase B (TrkB) pathway was previously associated with key oncogenic outcomes in a number of adenocarcinomas. The aim of our study was to determine the role ... -
Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae
(2015) [Artigo de periódico]This study assessed the occurrence and distribution of tropane alkaloids and calystegines in genera of the family Solanaceae to identify patterns of distribution and make evolutionary inferences. A database of tropane ... -
Trophic strategy of Atlantirivulus riograndensis (Cyprinodontiformes: Rivulidae), a non-annual rivulid threatened by extinction, in a perennial environment, Brazil)
(2016) [Artigo de periódico]Rivulidae includes non-annual fish of perennial habitats and annual fish of temporary wetlands. The objective of this research was to investigate the trophic strategy of Atlantirivulus riograndensis in a perennial environment. ... -
TSC1 and TSC2 gene mutations and their implications for tratment in tuberous sclerosis complex : a review
(2017) [Artigo de periódico]Tuberous sclerosis complex is an autosomal dominant disorder characterized by skin manifestations and formation of multiple tumors in different organs, mainly in the central nervous system. Tuberous sclerosis is caused by ... -
(TTTA)n polymorphism of CYP19 (aromatase gene) in Euro-and Afro-Brazilians
(2004) [Artigo de periódico]We investigated the polymorphic tetranucleotide repeat (TTTA)n located in the fourth intron of the CYP19 gene in two Brazilian populations. The frequencies of the five common alleles (A) in Euro- and Afro-Brazilians were, ... -
Tuberculosis in a southern Brazilian prison
(2012) [Artigo de periódico] -
Tuberculosis recurrence in a high incidence setting for HIV and tuberculosis in Brazil
(2014) [Artigo de periódico]Background: To compare epidemiological data between recurrent cases after cure (RC), distinguishing relapse from reinfection, after dropout (RD) and new cases (NC) in an ambulatory setting in a TB-endemic country. Methods: ... -
Tufted angioma in children : report of two cases and a review of the literature
(2014) [Artigo de periódico] -
TULP3 : a potential biomarker in colorectal cancer?
(2019) [Artigo de periódico]Colorectal cancer (CRC) is the second most common cancer in women and the third most common cancer in men globally. The identification of differentially expressed genes associated to patient’s clinical data may represent ... -
Tumor esofágico de células granulares associado à carcinoma epidermóide : relato de caso
(2013) [Artigo de periódico] -
Tumor-neutrophil crosstalk promotes in vitro and in vivo glioblastoma progression
(2023) [Artigo de periódico]Introduction: The tumor microenvironment (TME) of glioblastoma (GB) is characterized by an increased infiltration of immunosuppressive cells that attenuate the antitumor immune response. The participation of neutrophils ... -
Twenty years of the Fabry Outcome Survey (FOS) : insights, achievements, and lessons learned from a global patient registry
(2022) [Artigo de periódico]Background: Patient registries provide long-term, real-world evidence that aids the understanding of the natural history and progression of disease, and the efects of treatment on large patient populations with rare diseases. ... -
Twin peaks : a spatial and temporal study of twinning rates in Brazil
(2018) [Artigo de periódico]Twin births are an important public health issue due to health complications for both mother and children. While it is known that contemporary factors have drastically changed the epidemiology of twins in certain developed ... -
Twin town in south Brazil : a Nazi’s experiment or a genetic founder effect?
(2011) [Artigo de periódico]Cândido Godói (CG) is a small municipality in South Brazil with approximately 6,000 inhabitants. It is known as the ‘‘Twins’ Town’’ due to its high rate of twin births. Recently it was claimed that such high frequency of ... -
Two decades of colonization of the urban environment of Porto Alegre, southern Brazil, by Drosophila paulistorum (Diptera, Drosophilidae)
(2008) [Artigo de periódico]Drosophila paulistorum Dobzhansky & Pavan, 1949 era considerada inicialmente ausente em ambientes com influência antrópica, mas a detecção dessa espécie na cidade de Porto Alegre, sul do Brasil, em 1985, sugeriu seu potencial ... -
Two new species of Odontostilbe historically hidden under O. microcephala (Characiformes: Cheirodontinae)
(2018) [Artigo de periódico]Specimens historically identified as Odontostilbe microcephala from the upper rio Paraná and Andean piedmont tributaries of the río Paraguay are reviewed and split in three species. We found that the distribution of O. ... -
Two new troglobitic species of Scleropactidae (Crustacea: Isopoda: Oniscidea) from Pará, Brazil
(2011) [Artigo de periódico]The South America Scleropactidae includes 53 nominal species distributed in 14 genera. In Brazil, there are 16 species recorded in the north and southeast regions. Here, two new species of Scleropactidae are described based ... -
A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases
(2023) [Artigo de periódico]Cost-effective strategies for identifying amyloid-β (Aβ) positivity in patients with cognitive impairment are urgently needed with recent approvals of anti-Aβ immunotherapies for Alzheimer’s disease (AD). Blood biomarkers ... -
A two-tier bioinformatic pipeline to develop probes for target capture of nuclear loci with applications in Melastomataceae
(2020) [Artigo de periódico]Putatively single-copy nuclear (SCN) loci, which are identified using genomic resources of closely related species, are ideal for phylogenomic inference. However, suitable genomic resources are not available for many clades, ... -
Tympanic membrane retractions in patients with Williams Syndrome : a controlled study
(2021) [Artigo de periódico]Introduction The role of elastin in tympanic retractions and chronic otitis media is not well established. Williams Syndrome (WS), a pathology related to a mutation in the elastin gene, could generate tympanic retractions. ...
