Navegação Ciências Biológicas por Título
Resultados 1869-1888 de 3009
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N-acetylcysteine downregulates phosphorylated p-38 expression but does not reverse the increased superoxide anion levels in the spinal cord of rats with neuropathic pain
(2017) [Artigo de periódico]We determined the effect of N-acetylcysteine (NAC) on the expression of the phosphorylated p38 (p-p38) protein and superoxide anion generation (SAG), two important players in the processing of neuropathic pain, in the ... -
N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis
(2017) [Artigo de periódico]BACKGROUND Leishmaniasis is a parasitosis caused by several species of the genus Leishmania. These parasites present high resistance against oxidative stress generated by inflammatory cells. OBJECTIVES To investigate ... -
N-Acetylcysteine micronization by the seds technique using supercritical CO2
(2018) [Artigo de periódico]Abstract - N-Acetylcysteine (NAC) is a thiol (-SH) with a strong antioxidant activity. This compound has demonstrated positive effects on chronic kidney disease, cancer, pulmonary insufficiency and other diseases. The aim ... -
N-acetylcysteine protects against motor, optomotor and morphological deficits induced by 6-OHDA in zebrafish larvae
(2018) [Artigo de periódico]Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder. In addition to its highly debilitating motor symptoms, non-motor symptoms may precede their motor counterparts by many years, which ... -
Nanobacteria-like particles : a threat to cell cultures
(2007) [Artigo de periódico]The main goal of this study is to alert researchers who work with cell cultures for the risk of contamination by structures called nanobacteria (NB). NB are tiny structures with size varying from 80 to 500 nm, commonly ... -
Nanoemulsion improves the antifungal activity of allylic thiocyanates against yeasts and filamentous pathogenic fungi
(2018) [Artigo de periódico]We report the antifungal and antichemotactic activities of a series of allylic thiocyanates with low toxicity. We also show improved antifungal activity of the most promising compound when used in a nanoemulsion (NE). The ... -
Nanoformulation shows cytotoxicity against glioblastoma cell lines and antiangiogenic activity in chicken chorioallantoic membrane
(2021) [Artigo de periódico]Glioblastoma (GB) is a histological and genetically heterogeneous brain tumor that is highly proliferative and vascularized. The prognosis is poor with currently available treatment. In this study, we evaluated the ... -
Naringin supplementation during pregnancy induces sex and region-specific alterations in the offspring’s brain redox status
(2021) [Artigo de periódico]Research has shown the beneficial effects of naringin supplementation to adult rodents, which can ameliorate oxidative stress in disease models. However, evidence has demonstrated that polyphenol supplementation induced ... -
National Science and Technology Institute for Translational Medicine (INCT-TM) : advancing the field of translational medicine and mental health
(2010) [Artigo de periódico]Objetivo: Medicina translacional pode ser descrita como a aplicação integrada de ferramentas farmacológicas inovadoras, biomarcadores, métodos e tecnologias clínicas e delineamentos de pesquisa para aumentar o conhecimento ... -
Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population
(2020) [Artigo de periódico]Neuromyelitis Optica (NMO) is an autoimmune disease with a higher prevalence in non-European populations. Because the Mexican population resulted from the admixture between mainly Native American and European populations, ... -
Natural enemies of the Gall-maker Eugeniamyia dispar (Diptera, Cecidomyiidae): predatory ants and parasitoids
(2002) [Artigo de periódico]Natural enemies of the gall maker Eugeniamyia dispar (Diptera: Cecidomyiidae) were studied on the urban area of Porto Alegre, RS, Brazil from October 1993 to March 1996. Galls and associated arthropods were followed weekly ... -
Natural plant alkaloid (Emetine) inhibits HIV-1 replication by interfering with reverse transcriptase activity.
(2015) [Artigo de periódico]Ipecac alkaloids are secondary metabolites produced in the medicinal plant Psychotria ipecacuanha. Emetine is the main alkaloid of ipecac and one of the active compounds in syrup of Ipecac with emetic property. Here we ... -
Nature of insoluble material found in the bottom of soybean biodiesel storage tank : chemical and microbiological approach
(2018) [Artigo de periódico]During biodiesel storage, chemical reactions may occur, producing sludges. The aim of this study was to characterize the chemical and microbial composition of the sludge found in a biodiesel storage tank. The material was ... -
Neoadjuvant multikinase inhibitor in patients with locally advanced unresectable thyroid carcinoma
(2019) [Artigo de periódico]Background: Papillary thyroid carcinoma (PTC) is the most common and less aggressive thyroid cancer, but some patients may display locally advanced disease. Therapeutic options are limited in these cases, particularly for ... -
Neonatal handling and the expression of immunoreactivity to tyrosine hydroxylase in the hypothalamus of adult male rats
(2001) [Artigo de periódico]Neonatal handling has long-lasting effects on behavior and stress reactivity. The purpose of the present study was to investigate the effect of neonatal handling on the number of dopaminergic neurons in the hypothalamic ... -
Neonatal handling induces anovulatory estrous cycles in rats
(1999) [Artigo de periódico] -
Neonatal screening for congenital adrenal hyperplasia in Southern Brazil : a population based study with 108,409 infants
(2017) [Artigo de periódico]Background: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder associated with inborn errors of steroid metabolism. 21-hydroxylase enzyme deficiency occurs in 90 to 95% of all cases of CAH, with ... -
Neonatal screening for four lysosomal storage diseases with a digital microfluidics platform: initial results in Brazil
(2018) [Artigo de periódico]We describe the initial results of a neonatal screening program for four lysosomal storage diseases (MPS I, Pompe, Gaucher and Fabry) using the digital microfluidics methodology. The method successfully identified patients ... -
Neonatal screening for MPS disorders in Latin America : a survey of pilot initiatives
(2020) [Artigo de periódico]Newborn screening enables the diagnosis of treatable disorders at the early stages, and because of its countless benefits, conditions have been continuously added to screening panels, allowing early intervention, aiming ...