Navegação Ciências Biológicas por Título
Resultados 1122-1141 de 3042
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Exosomes : small EVs with large immunomodulatory effect in glioblastoma
(2021) [Artigo de periódico]Glioblastomas are among the most aggressive tumors, and with low survival rates. They are characterized by the ability to create a highly immunosuppressive tumor microenvironment. Exosomes, small extracellular vesicles ... -
Experience of the NPC Brazil network with a comprehensive program for the screening and diagnosis of Niemann-Pick disease type C
(2022) [Artigo de periódico]Niemann-Pick disease type C (NPC) is a lysosomal disorder caused by impaired cholesterol metabolism. Levels of lysosphingomyelin 509 (LysoSM509) have been shown elevated in dried blood spots (DBS) of NPC and acid ... -
Uma experiência terapêutica no manejo da doença da urina do xarope do bordo
(1995) [Artigo de periódico]Relata-se aqui o manejo terapêutico realizado em um paciente portador da Doença da Urina do Xarope de Bordo, com diagnóstico e encaminhamento tardios (2 e 5 meses). Uma vez que o paciente apresentava níveis extremamente ... -
Experimental infection of rabbits with a recombinant bovine herpesvirus type 5 (BoHV-5) gI, gE and US9-negative
(2009) [Artigo de periódico]O herpesvírus bovino tipo 5 é uma das principais causas de meningoencefalite viral em bovinos. A expressão de diferentes proteínas virais tem sido associada à neuropatogenia do BoHV-5. Entre estas, a gI, gE e US9 têm sido ... -
Experimental model of gene transfection in healthy canine myocardium. Perspectives of gene therapy for ischemic heart disease
(2002) [Artigo de periódico]Objective - To assess the transfection of the gene that encodes green fluorescent protein (GFP) through direct intramyocardial injection. Methods - The pREGFP plasmid vector was used. The EGFP gene was inserted downstream ... -
Expert range maps of global mammal distributions harmonised to three taxonomic authorities
(2022) [Artigo de periódico]Aim: Comprehensive, global information on species' occurrences is an essential biodiversity variable and central to a range of applications in ecology, evolution, biogeography and conservation. Expert range maps often ... -
Explorando a bacia hidrográfica na escola : contribuições à educação ambiental
(2008) [Artigo de periódico]Este trabalho foi desenvolvido em duas escolas públicas do município de Giruá, RS, com a participação de professores e estudantes dos Ensinos Fundamental e Médio, com ênfase na sub-bacia do Rio Santo Cristo. Os procedimentos ... -
Exploration of the Yield Potential of Mesoamerican Wild Common Beans From Contrasting Eco-Geographic Regions by Nested Recombinant Inbred Populations
(2020) [Artigo de periódico]Genetic analyses and utilization of wild genetic variation for crop improvement in common bean (Phaseolus vulgaris L.) have been hampered by yield evaluation difficulties, identification of advantageous variation, and ... -
Exploring CD39 and CD73 expression as potential biomarkers in prostate cancer
(2023) [Artigo de periódico]Prostate cancer (PC) is the most diagnosed tumor in males and ranks as the second leading cause of male mortality in the western world. The CD39 and CD73 enzymes play a crucial role in cancer regulation by degrading ... -
Exploring facial thermography patterns in women with chronic migraine
(2023) [Artigo de periódico](1) Background: Chronic migraine is a debilitating neurological condition affecting millions worldwide. This study delves into the facial point-of-care (POC) thermographic patterns of women with chronic migraine, aiming ... -
Exploring potential impacts of pregnancy-related maternal immune activation and extracellular vesicles on immune alterations observed in autism spectrum disorder
(2023) [Artigo de periódico]Autism Spectrum Disorder (ASD) is a set of neurodevelopmental disorders usually observed in early life, with impacts on behavioral and social skills. Incidence of ASD has been dramatically increasing worldwide, possibly ... -
Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas
(2023) [Artigo de periódico]The TP53 3’UTR variant rs78378222 A>C has been detected in different tumor types as a somatic alteration that reduces p53 expression through modification of polyadenylation and miRNA regulation. Its prevalence is not yet ... -
A exposição pré-natal ao álcool como fator de risco para comportamentos disfuncionais : o papel do pediatra
(2008) [Artigo de periódico]Objetivo: Ainda que as características clássicas da síndrome fetal alcoólica tenham sido descritas desde 1968, a pesquisa sobre a teratogênese do álcool apenas recentemente demonstrou que o cérebro é o órgão do corpo mais ... -
Expressão de neurotrofinas e de seus receptores no osteossarcoma primário
(2019) [Artigo de periódico]Objetivo: determinar a expressão de neurotrofinas e seus receptores tirosina quinases em pacientes com osteossarcoma (OS) e sua correlação com desfechos clínicos. Métodos: biópsias de tumores primários de pacientes com OS ... -
Expressão dos protooncogenes C-FOS, C-MYC e C-JUN em miométrio normal e mioma humanos
(2006) [Artigo de periódico]Objetivo: Comparar a expressão gênica (mRNA) e protéica dos protooncogenes c-fos, c-myc e c-jun em miométrio normal e mioma humanos. Métodos: Foi realizado um estudo do tipo caso-controle. O material foi coletado de 12 ... -
Expressão gênica das células do cumulus oophorus de bovinos após vitrificação
(2010) [Artigo de periódico]Um dos desafios da criobiologia continua sendo o desenvolvimento de um método que proporcione a manutenção da viabilidade após a criopreservação de oócitos imaturos na espécie bovina. A vitrificação tem sido a metodologia ... -
Expression of an osmotin-like protein from Solanum nigrum confers drought tolerance in transgenic soybean
(2014) [Artigo de periódico]Background: Drought is by far the most important environmental factor contributing to yield losses in crops, including soybeans [Glycine max (L.) Merr.]. To address this problem, a gene that encodes an osmotin-like protein ... -
Expression of matrix metalloproteinases in patients with bipolar disorder
(2013) [Artigo de periódico]Objective: High cardiovascular mortality rates have been reported in patients with bipolar disorder (BD). Studies indicate that matrix metalloproteinases (MMPs) are implicated in cardiovascular diseases. We evaluated the ... -
Expression of mdr isoforms in mice during estrous cycle and under hormone stimulation
(2006) [Artigo de periódico]The multidrug resistance (MDR) phenotype is associated with the expression of P-glycoprotein (Pgp), coded by the multigenic mdr family. Mice present the isoforms mdr1 and mdr3, which are responsible for multidrug resistance, ... -
Expression of the bacterial recA gene impairs genetic recombination and sporulation in a Saccharomyces cerevisae diploid strain
(2003) [Artigo de periódico]The Escherichia coli RecA protein (RecAp) has been demonstrated to induce mutagenesis in yeast cells, although there is still little information on the role of the RecAp in yeast recombination events. We evaluated spontaneous ...