Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests
dc.contributor.author | Falci, Diego Rodrigues | pt_BR |
dc.contributor.author | Hoffmann, Elias da Rosa | pt_BR |
dc.contributor.author | Paskulin, Diego D'Ávila | pt_BR |
dc.contributor.author | Pasqualotto, Alessandro Comaru | pt_BR |
dc.date.accessioned | 2018-11-30T02:42:50Z | pt_BR |
dc.date.issued | 2017 | pt_BR |
dc.identifier.issn | 1413-8670 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/185282 | pt_BR |
dc.description.abstract | The diagnosis of progressive disseminated histoplasmosis is often a challenge to clinicians,especially due to the low sensitivity and long turnaround time of the classic diagnostic meth-ods. In recent years, studies involving a variety of non-culture-based diagnostic tests havebeen published in the literature. We performed a systematic review by selecting studies eval-uating non-culture-based diagnostic methods for progressive disseminated histoplasmosis.We searched for articles evaluating detection of antibody, antigens, as well as DNA-baseddiagnostic methods. A comprehensive PUBMED, Web of Science, and Cochrane Librarysearch was performed between the years 1956 and 2016. Case reports, review articles, non-human models and series involving less than 10 patients were excluded. We found 278articles and after initial review 18 articles were included: (12) involved antigen detectionmethods, (4) molecular methods, and (2) antibody detection methods. Here we demonstratethat the pursuit of new technologies is ultimately required for the early and accurate diag-nosis of disseminated histoplasmosis. In particular, urinary antigen detection was the mostaccurate tool when compared with other diagnostic techniques. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | The Brazilian journal of infectious diseases. Salvador. Vol. 21, n. 1 (Jan.-Feb. 2017), p. 7-11 | pt_BR |
dc.rights | Open Access | en |
dc.subject | Disseminated histoplasmosis | en |
dc.subject | Histoplasmose | pt_BR |
dc.subject | Diagnóstico | pt_BR |
dc.subject | Non-culture | en |
dc.subject | Enzyme immunoassay | en |
dc.subject | Técnicas imunoenzimáticas | pt_BR |
dc.subject | Reação em cadeia da polimerase | pt_BR |
dc.subject | Diagnostic testsa | en |
dc.subject | Métodos | pt_BR |
dc.subject | Sensibilidade e especificidade | pt_BR |
dc.subject | Testes sorológicos | pt_BR |
dc.title | Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 001080457 | pt_BR |
dc.type.origin | Nacional | pt_BR |
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