Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity

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Date
2016
Author
Advisor
Academic level
Graduation
Type
URI
http://hdl.handle.net/10183/184776
Subject
Abstract
A new series of 4-methyl-quinolines was synthesized as potential cruzain inhibitors using Doebner-Von Miller synthesis. The compounds (1a-f) are undergoing analysis in order to guarantee their purities and further explore their biological activity.
Institution
Universidade Federal do Rio Grande do Sul. Faculdade de Farmácia. Curso de Farmácia.
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