Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity

dc.contributor.advisor	Gnoatto, Simone Cristina Baggio	pt_BR
dc.contributor.author	Santos, Eduardo da Silveira dos	pt_BR
dc.date.accessioned	2018-11-17T03:12:08Z	pt_BR
dc.date.issued	2016	pt_BR
dc.identifier.uri	http://hdl.handle.net/10183/184776	pt_BR
dc.description.abstract	A new series of 4-methyl-quinolines was synthesized as potential cruzain inhibitors using Doebner-Von Miller synthesis. The compounds (1a-f) are undergoing analysis in order to guarantee their purities and further explore their biological activity.	en
dc.format.mimetype	application/pdf	pt_BR
dc.language.iso	eng	pt_BR
dc.rights	Open Access	en
dc.subject	Quinoline	en
dc.subject	Farmácia	pt_BR
dc.subject	Doebner-Von Miller	en
dc.subject	Cruzain	en
dc.subject	Trypanosoma cruzi	en
dc.subject	Chagas disease	en
dc.title	Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity	pt_BR
dc.type	Trabalho de conclusão de graduação	pt_BR
dc.identifier.nrb	001020636	pt_BR
dc.degree.grantor	Universidade Federal do Rio Grande do Sul	pt_BR
dc.degree.department	Faculdade de Farmácia	pt_BR
dc.degree.local	Porto Alegre, BR-RS	pt_BR
dc.degree.date	2016	pt_BR
dc.degree.graduation	Farmácia	pt_BR
dc.degree.level	graduação	pt_BR

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