Body fat percentage, cardiorespiratory ftness and arterial blood pressure in children and adolescents : a longitudinal analysis

Abstract

Background: A better understanding of how cardiorespiratory ftness (CRF) and adiposity interact to associate with arterial blood pressure over time remains inconclusive. Thus, the aim of the present study was to examine whether changes in CRF moderates the association between body fat percentage (BF%) and arterial blood pressure in children and adolescents. Methods: This is an observational longitudinal study with 407 children and adolescents aged 8–17 years followed-up for three years from a city in Southern Brazil. Participants were evaluated in 2011 and 2014. CRF was measured by validated feld-based tests following the Projeto Esporte Brazil protocols and peak oxygen uptake (VO2peak) was estimated. BF% was determined by the measures of tricipital and subscapular skinfolds using equations according to sex. Systolic and diastolic blood pressure (SBP, DBP) were measured with a sphygmomanometer according to standard procedures. Moderation analyses included multiple linear regression models adjusted for sex, age, pubertal status, height, socioeconomic level, skin color, and the arterial blood pressure variable itself at baseline. Results: It was observed a signifcant inverse association between VO2peak at baseline with SBP (β=−0.646 CI95%=−0.976 −0.316) and DBP (β=−0.649 CI95%=−0.923 −0.375) at follow-up and a positive association between BF% at baseline with SBP (β=0.274; CI95%=0.094 0.455) and DBP (β=0.301; CI95%=0.150 0.453) at follow-up. In addition, results indicated a signifcant interaction term between changes in VO2peak and BF% at baseline with both SBP (p=0.034) and DBP at follow-up (p=0.011), indicating that an increase of at least 0.35 mL/kg/min and 1.78 mL/kg/min in VO2peak attenuated the positive relationship between BF% with SBP and DBP. Conclusion: CRF moderates the relationship between BF% and SBP and DBP in children and adolescents.