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dc.contributor.authorComerlato, Pedro Henriquept_BR
dc.contributor.authorStefani, Joelpt_BR
dc.contributor.authorViana, Marina Verçozapt_BR
dc.contributor.authorViana, Luciana Verçozapt_BR
dc.date.accessioned2023-03-10T03:26:15Zpt_BR
dc.date.issued2020pt_BR
dc.identifier.issn1413-8670pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/255514pt_BR
dc.description.abstractIntroduction: Malnutrition is associated with an increased risk of complications in hospi- talized patients, and parenteral nutrition (PN) is used when oral or enteral feeding is not possible. This study aimed at analyzing associations between PN characteristics and infec- tious complications in hospitalized patients. Material and methods: This was a retrospective cohort study conducted in a tertiarycare university hospital. Data from consecutive adult patients submitted to PN (January 2016 to December 2017; ICU and ward) were reviewed by means of an electronic database. Patient’s clinical characteristics, PN prescription and catheter insertion procedure data were extracted and analyzed. The main outcome was the development of central line–associated bloodstream infection (CLABSI). The secondary outcomes were other infectious complica- tions and mortality, as well as factors associated with CLABSI. Results: We analyzed 165 patients and 247 catheters used for parenteral nutrition infusion. The CLABSI rate was 6.47 per 1000 catheter-days. In the univariable analysis, CLABSI was associated with longer hospitalization time, longer PN time, longer catheter time, catheter insertion performed by a surgeon or a surgical resident, and procedures performed outside the ICU. In an extended time-dependent Cox regression, no variable was associated with a higher risk of CLABSI, and additional PN days did not increase the rate of CLABSI. The overall mortality rate was 24.8%. Only the patients’ comorbidity index was associated with death in the multivariable analysis.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofThe Brazilian journal of infectious diseases. Salvador. Vol. 24, no. 2 (2020), p. 137-143pt_BR
dc.rightsOpen Accessen
dc.subjectParenteral nutritionen
dc.subjectInfecção hospitalarpt_BR
dc.subjectCatheteren
dc.subjectNutrição parenteralpt_BR
dc.subjectUnidades de terapia intensivapt_BR
dc.subjectCentral venous catheteren
dc.subjectCLABSIen
dc.subjectCateteres venosos centraispt_BR
dc.subjectHospital-acquired infectionen
dc.titleInfectious complications associated with parenteral nutrition in intensive care unit and non-intensive care unit patientspt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001159801pt_BR
dc.type.originNacionalpt_BR


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