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Pharmacological properties of specioside from the stem bark of Tabebuia aurea

dc.contributor.authorNocchi, Samara Requenapt_BR
dc.contributor.authorKato, Natália Naomipt_BR
dc.contributor.authorAlmeida, Júlio Menta dept_BR
dc.contributor.authorFerreira, Alda Maria Teixeirapt_BR
dc.contributor.authorKadri, Mônica Cristina Toffolipt_BR
dc.contributor.authorMeirelles, Lyvia Eloiza de Freitaspt_BR
dc.contributor.authorDamke, Gabrielle Marconi Zago Ferreirapt_BR
dc.contributor.authorConsolaro, Márcia Edilaine Lopespt_BR
dc.contributor.authorRigo, Graziela de Vargaspt_BR
dc.contributor.authorMacedo, Alexandre Josépt_BR
dc.contributor.authorTasca, Tianapt_BR
dc.contributor.authorReis, Sharon Vieira dospt_BR
dc.contributor.authorAlves, Flávio Macedopt_BR
dc.contributor.authorCarollo, Carlos Alexandrept_BR
dc.contributor.authorSilva, Denise Brentanpt_BR
dc.date.accessioned2020-12-24T04:21:26Zpt_BR
dc.date.issued2020pt_BR
dc.identifier.issn0102-695Xpt_BR
dc.identifier.urihttp://hdl.handle.net/10183/216877pt_BR
dc.description.abstractIridoids are secondary metabolites with several biological activities. They are often found in species of the genus Tabebuia Gomes ex A.P. de Candolle. Tabebuia aurea (Silva Manso) Benth. & Hook. F. ex S. Moore, Bignoniaceae, is used to treat snake bites in traditional medicine. This study aimed to isolate the specioside - an the iridoid glycoside - from T. aurea, as well as investigate its potential biological properties, including anti-inflammatory, antibacterial, antibiofilm, cytotoxic, anti-Trichomonas vaginalis and antitrypanosomal activities. Specioside inhibited leucocyte recruitment into the peritoneal cavity in mice injected with carrageenan, data that demonstrated its anti-inflammatory potential. However, the additional evaluated biological properties were negligible.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofRevista brasileira de farmacognosia. Vol. 30 (2020), p. 118-122pt_BR
dc.rightsOpen Accessen
dc.subjectIridoidespt_BR
dc.subjectIridoiden
dc.subjectAnti-inflammatoryen
dc.subjectAnti-inflamatóriospt_BR
dc.subjectChemical identificationen
dc.subjectCitotoxinaspt_BR
dc.subjectLeucocyte recruitmenten
dc.subjectCytotoxicen
dc.titlePharmacological properties of specioside from the stem bark of Tabebuia aureapt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001120023pt_BR
dc.type.originNacionalpt_BR


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