Pharmacological properties of specioside from the stem bark of Tabebuia aurea
dc.contributor.author | Nocchi, Samara Requena | pt_BR |
dc.contributor.author | Kato, Natália Naomi | pt_BR |
dc.contributor.author | Almeida, Júlio Menta de | pt_BR |
dc.contributor.author | Ferreira, Alda Maria Teixeira | pt_BR |
dc.contributor.author | Kadri, Mônica Cristina Toffoli | pt_BR |
dc.contributor.author | Meirelles, Lyvia Eloiza de Freitas | pt_BR |
dc.contributor.author | Damke, Gabrielle Marconi Zago Ferreira | pt_BR |
dc.contributor.author | Consolaro, Márcia Edilaine Lopes | pt_BR |
dc.contributor.author | Rigo, Graziela de Vargas | pt_BR |
dc.contributor.author | Macedo, Alexandre José | pt_BR |
dc.contributor.author | Tasca, Tiana | pt_BR |
dc.contributor.author | Reis, Sharon Vieira dos | pt_BR |
dc.contributor.author | Alves, Flávio Macedo | pt_BR |
dc.contributor.author | Carollo, Carlos Alexandre | pt_BR |
dc.contributor.author | Silva, Denise Brentan | pt_BR |
dc.date.accessioned | 2020-12-24T04:21:26Z | pt_BR |
dc.date.issued | 2020 | pt_BR |
dc.identifier.issn | 0102-695X | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/216877 | pt_BR |
dc.description.abstract | Iridoids are secondary metabolites with several biological activities. They are often found in species of the genus Tabebuia Gomes ex A.P. de Candolle. Tabebuia aurea (Silva Manso) Benth. & Hook. F. ex S. Moore, Bignoniaceae, is used to treat snake bites in traditional medicine. This study aimed to isolate the specioside - an the iridoid glycoside - from T. aurea, as well as investigate its potential biological properties, including anti-inflammatory, antibacterial, antibiofilm, cytotoxic, anti-Trichomonas vaginalis and antitrypanosomal activities. Specioside inhibited leucocyte recruitment into the peritoneal cavity in mice injected with carrageenan, data that demonstrated its anti-inflammatory potential. However, the additional evaluated biological properties were negligible. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Revista brasileira de farmacognosia. Vol. 30 (2020), p. 118-122 | pt_BR |
dc.rights | Open Access | en |
dc.subject | Iridoides | pt_BR |
dc.subject | Iridoid | en |
dc.subject | Anti-inflammatory | en |
dc.subject | Anti-inflamatórios | pt_BR |
dc.subject | Chemical identification | en |
dc.subject | Citotoxinas | pt_BR |
dc.subject | Leucocyte recruitment | en |
dc.subject | Cytotoxic | en |
dc.title | Pharmacological properties of specioside from the stem bark of Tabebuia aurea | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 001120023 | pt_BR |
dc.type.origin | Nacional | pt_BR |
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