The Hematopoietic stroma

dc.contributor.author	Nardi, Nance Beyer	pt_BR
dc.contributor.author	Alfonso, Zeni Zoraia da Costa	pt_BR
dc.date.accessioned	2010-04-24T04:15:31Z	pt_BR
dc.date.issued	1999	pt_BR
dc.identifier.issn	0100-879X	pt_BR
dc.identifier.uri	http://hdl.handle.net/10183/21156	pt_BR
dc.description.abstract	All blood cells are derived from a small common pool of totipotent cells, called hematopoietic stem cells. The process is strictly regulated by the hematopoietic microenvironment, which includes stromal cells, extracellular matrix molecules and soluble regulatory factors. Several experimental in vitro assays have been developed for the study of hematopoietic differentiation, and have provided valuable information on the stroma, which includes, among other cell types, macrophages, fibroblasts, adipocytes, and endothelial cells. The composition, ontogeny, and function in physiological as well as pathological conditions of stroma are discussed.	en
dc.format.mimetype	application/pdf
dc.language.iso	eng	pt_BR
dc.relation.ispartof	Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas. Ribeirão Preto, SP. Vol. 32, no. 5 (May 1999), p. 601-609.	pt_BR
dc.rights	Open Access	en
dc.subject	Genética	pt_BR
dc.subject	Hematopoiesis	en
dc.subject	Microenvironment	en
dc.subject	Stroma	en
dc.title	The Hematopoietic stroma	pt_BR
dc.type	Artigo de periódico	pt_BR
dc.identifier.nrb	000295680	pt_BR
dc.type.origin	Nacional	pt_BR

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