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dc.contributor.authorBlotta, Rosa Mariapt_BR
dc.contributor.authorCosta, Sirlei dos Santospt_BR
dc.contributor.authorTrindade, Eduardo Neubarthpt_BR
dc.contributor.authorMeurer, Luísept_BR
dc.contributor.authorTrindade, Manoel Roberto Macielpt_BR
dc.date.accessioned2019-10-10T03:49:55Zpt_BR
dc.date.issued2018pt_BR
dc.identifier.issn1980-5322pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/200389pt_BR
dc.description.abstractOBJECTIVES: Interest in elucidating the etiology of hernias has encouraged countless studies of musculoaponeurotic structures in individuals with and without hernias. Studies of hernia patients have firmly demonstrated a correlation between hernias and collagen alterations in their fascia. Diastasis recti is an increased width of the abdominal midline that is exclusively composed of interlacing aponeurotic expansions of the anterolateral abdominal muscles. The condition is common among women undergoing abdominoplasty, and many factors, not only mechanical, play a role. The goal of this study is to evaluate and compare collagen type I and III levels in the midline fascia of women with and without diastasis recti to report their possible influence on this condition. METHODS: This is a case-control study nested within a surgical cohort of 18 women with diastasis recti and 18 women without the condition (cases and controls, respectively). Fascia from the midline of the abdominal wall was collected and analyzed through immunohistochemistry using polyclonal antibodies to collagen type I and III. RESULTS: Both type I and type III collagen were less abundant in women with diastasis recti than in those without the condition, and the difference was statistically significant (po0.001). CONCLUSION: Low collagen type I and type III levels in the midline of the abdominal wall may play a key role in the development of diastasis recti.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofClinics. São Paulo. Vol. 73 (June 2018), e319, 5 p.pt_BR
dc.rightsOpen Accessen
dc.subjectAbdominal wallen
dc.subjectParede abdominalpt_BR
dc.subjectLinea albaen
dc.subjectHérniapt_BR
dc.subjectDiastasis rectien
dc.subjectColágeno tipo Ipt_BR
dc.subjectColágeno tipo IIIpt_BR
dc.subjectType I Collagenen
dc.subjectFásciapt_BR
dc.subjectType III Collagenen
dc.subjectMulherespt_BR
dc.titleCollagen I and III in women with diastasis rectipt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001102517pt_BR
dc.type.originNacionalpt_BR


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