Navegação Ciências da Saúde por Assunto "C3H/HeJ and C57BL/6J"

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Abnormal thyroid hormone status differentially affects bone mass accrual and bone strength in C3H/HeJ mice: a mouse model of type I deiodinase deficiency

Zaitune, Clarissa R.; Fonseca, Tatiana de Lourdes; Capelo, Luciane Portas; Freitas, Fatima Rodrigues de Sousa e; Beber, Eduardo Henrique; Dora, José Miguel Silva; Wang, Charles Chenwei; Rodrigues, Manuela Miranda; Nonaka, Keico Okino; Maia, Ana Luiza Silva; Gouveia, Cecilia H. A. (2019) [Artigo de periódico]

C3H/HeJ (C3H) mice are deficient of type I deiodinase (D1), an enzyme that activates thyroid hormone (TH), converting thyroxine (T4) to triiodothyronine (T3). Nevertheless, C3H mice present normal serum T3 and a gross ...