Ciências Biológicas: Últimas Submissões
Resultados 21-30 de 3508
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The evolution of randomized clinical trial designs to assess therapeutics in Alzheimer disease
(2025) [Artigo de periódico]IMPORTANCE: The success of recent randomized clinical trials (RCTs) for Alzheimer disease (AD), particularly those focusing on anti-amyloid therapies, has been discussed at length. However, the evolution of RCT design ... -
Downregulation of miR-27a-3p modulates TGF-β signaling and dysregulates metabolism in glioblastoma
(2025) [Artigo de periódico]Several microRNAs (miRNAs) are key influencers of tumor microenvironment (TME) cell plasticity, regulating the progression of various tumor types such as glioblastoma (GBM). Differential expressions of miR-27a-3p and ... -
Glial reactivity correlates with synaptic dysfunction across aging and Alzheimer’s disease
(2025) [Artigo de periódico]Previous studies suggest glial and neuronal changes may trigger synaptic dysfunction in Alzheimer’s disease (AD), but the link between their markers and synaptic abnormalities in the living brain remains unclear. We ... -
Why should lymphocytes immune profile matter in sepsis?
(2025) [Artigo de periódico]The global incidence of critical illness has been steadily increasing, resulting in higher mortality rates thereby presenting substantial challenges for clinical management. Among these conditions, sepsis stands out as the ... -
Validation of a traditional medicine, Achyrocline satureioides infusion, for the improvement of mild respiratory infection symptoms : a randomized, placebo-controlled and open-label clinical trial
(2025) [Artigo de periódico]The need for the scientific validation of traditional and folk medicine knowledge has emerged lately. Achyrocline satureioides inflorescences have been widely used for the management of mild viral respiratory infection ... -
Unveiling the cardiovascular impact of Zika Virus : myocardial injury, prothrombotic state, and oxidative stress in immunocompetent mice
(2025) [Artigo de periódico]The Zika virus (ZIKV) has been associated with neurological and cardiovascular complications, including myocarditis, arrhythmias and thrombotic events. This study evaluated the thrombotic and oxidative responses induced ... -
Ostracodes batíbicos do Brasil : história, críticas e perspectivas
(2024) [Artigo de periódico] -
Drug repurposing and personalized treatment strategies for bipolar disorder using transcriptomics : an exploratory study
(2024) [Artigo de periódico]Objective: The present study combined transcriptomic data and computational techniques based on gene expression signatures to identify new bioactive compounds or Food and Drug Administrationapproved drugs for the treatment ... -
Gengivite plasmocitaria
(1992) [Artigo de periódico]É feita uma revisão bibliográfica sobre lesões não tumorais plasmocitárias procurando caracterizá-las clínica e histopatológicamente. É apresentado um caso de gengivite plasmocitária. -
Ainda sobre agulhas e pincéis : novas reflexões sobre a Ostracodologia e os ostracodologistas
(2025) [Artigo de periódico]Introduction. This paper addresses the history of Ostracodology – the study of ostracods, tiny crustaceans with bivalve shells – adapted to various aquatic and even humid terrestrial environments. Objective. To examine the ...