Navegação Ciências Biológicas por Assunto "Rapamycin"

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    • Primary cells derived from Tuberous Sclerosis Complex patients show autophagy alteration in the haploinsufficiency state 

      Rosset, Clévia; Jaeger, Mariane da Cunha; Chiela, Eduardo Cremonese Filippi; Reis, Larissa Brussa; Sartor, Ivaine Tais Sauthier; Netto, Cristina Brinckmann Oliveira; Farias, Caroline Brunetto de; Roesler, Rafael; Prolla, Patrícia Ashton (2021) [Artigo de periódico]
      Tuberous sclerosis complex (TSC) is an autosomal dominant cancer predisposition disorder caused by heterozygous mutations in TSC1 or TSC2 genes and characterized by mTORC1 hyperactivation. TSC-associated tumors develop ...