• Cholinergic immunomodulation in inflammatory bowel diseases 

      Serafini, Michele Aramburu; Paz, Ana Helena da Rosa; Nunes, Natália Schneider (2022) [Artigo de periódico]
      Inflammatory bowel diseases (IBD) are chronic intestinal disorders characterized by dysregulated immune responses to resident microbiota in genetically susceptible hosts. The activation of the cholinergic system has been ...
    • Effects of living and metabolically inactive mesenchymal stromal cells and their derivatives on monocytes and macrophages 

      Sant'Ana, Alexia Nedel; Araujo, Anelise Bergmann; Gonçalves, Fabiany da Costa; Paz, Ana Helena da Rosa (2021) [Artigo de periódico]
      Mesenchymal stromal cells (MSCs) are multipotent and self-renewing stem cells that have great potential as cell therapy for autoimmune and inflammatory disorders, as well as for other clinical conditions, due to their ...
    • Elevated holo-transcobalamin in Gaucher disease type II : a case report 

      Basgalupp, Suelen Porto; Donis, Karina Carvalho; Siebert, Marina; Vairo, Filippo Pinto e; Artigalas, Osvaldo Alfonso Pinto; Pinto, Louise Lapagesse de Camargo; Behringer, Sidney; Spiekerkotter, Ute; Hannibal, Luciana; Schwartz, Ida Vanessa Doederlein (2021) [Artigo de periódico]
      Gaucher disease (GD), one of the most common lysosomal disorders, is caused by deficiency of β-glucocerebrosidase. Based on the presence and severity of neurological complications, GD is classified into types I, II (the ...
    • Transcriptomic analysis reveals that mTOR pathway can be modulated in macrophage cells by the presence of cryptococcal cells 

      Piffer, Alicia Corbellini; Santos, Francine Melise dos; Thomé, Marcos Paulo; Rosa, Camila Diehl da; Garcia, Ane Wichine Acosta; Kinskovski, Uriel Perin; Schneider, Rafael de Oliveira; Gerber, Alexandra Lehmkuhl; Feltes, Bruno César; Schrank, Augusto; Vasconcelos, Ana Tereza Ribeiro de; Lenz, Guido; Silva, Lívia Kmetzsch Rosa e; Vainstein, Marilene Henning; Staats, Charley Christian (2021) [Artigo de periódico]
      Cryptococcus neoformans and Cryptococcus gattii are the etiological agents of cryptococcosis, a high mortality disease. The development of such disease depends on the interaction of fungal cells with macrophages, in which ...