• Antidepressant-like effects of chronic guanosine in the olfactory bulbectomy mouse model 

      Almeida, Roberto Farina de; Nonose, Yasmine; Ganzella, Marcelo; Loureiro, Samanta Oliveira; Rocha, Andréia Silva da; Machado, Daniele Guilhermano; Bellaver, Bruna; Fontella, Fernanda Urruth; Leffa, Douglas Teixeira; Pettenuzzo, Letícia Ferreira; Venturin, Gianina Teribele; Greggio, Samuel; Costa, Jaderson Costa da; Zimmer, Eduardo Rigon; Elisabetsky, Elaine; Souza, Diogo Onofre Gomes de (2021) [Artigo de periódico]
      Major depressive disorder (MDD) leads to pervasive changes in the health of afflicted patients. Despite advances in the understanding of MDD and its treatment, profound innovation is needed to develop fast-onset antidepressants ...
    • Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model 

      Almeida, Roberto Farina de; Barbosa, Camila Pocharski; Rodrigues, Ana Lucia Severo; Elisabetsky, Elaine; Souza, Diogo Onofre Gomes de (2020) [Artigo de periódico]
      The treatment of major depressive disorder (MDD) is still a challenge. In the search for novel antidepressants, glutamatergic neuromodulators have been investigated as possible fast-acting antidepressants. Innovative studies ...
    • Maturation of pyramidal cells in anterior piriform cortex may be sufficient to explain the end of early olfactory learning in rats 

      Puma, Enver Miguel Oruro; Pardo, Grace Violeta Espinoza; Lucion, Aldo Bolten; Calcagnotto, Maria Elisa; Idiart, Marco Aurelio Pires (2020) [Artigo de periódico]
      Studies have shown that neonate rodents exhibit high ability to learn a preference for novel odors associated with thermotactile stimuli that mimics maternal care. Artificial odors paired with vigorous strokes in rat pups ...
    • The maturational characteristics of the GABA input in the anterior piriform cortex may also contribute to the rapid learning of the maternal odor during the sensitive period 

      Puma, Enver Miguel Oruro; Pardo, Grace Violeta Espinoza; Lucion, Aldo Bolten; Calcagnotto, Maria Elisa; Idiart, Marco Aurelio Pires (2020) [Artigo de periódico]
      During the first ten postnatal days (P), infant rodents can learn olfactory preferences for novel odors if they are paired with thermo-tactile stimuli that mimic components of maternal care. After P10, the thermo-tactile ...
    • The neurobiology of infant maternal odor learning 

      Raineki, Charlis; Pickenhagen, Anouchka; Roth, Tania L.; Babstock, Doris M.; McLean, John H.; Harley, Carolyn W.; Lucion, Aldo Bolten; Sullivan, Regina M. (2010) [Artigo de periódico]
      Infant rats must learn to identify their mother’s diet-dependent odor. Once learned, maternal odor controls pups’ approach to the mother, their social behavior and nipple attachment. Here we present a review of the research ...