Navegação Ciências Biológicas por Assunto "Acetilcisteína"
Resultados 1-7 de 7
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Anxiolytic properties of compounds that counteract oxidative stress, neuroinflammation, and glutamatergic dysfunction : a review
(2019) [Artigo de periódico]Objective: Anxiety disorders are highly prevalent and the efficacy of the available anxiolytic drugs is less than desired. Adverse effects also compromise patient quality of life and adherence to treatment. Accumulating ... -
Effects of N-acetylcysteine on amphetamine-induced sensitization in mice
(2018) [Artigo de periódico]N-acetylcysteine (NAC) is beneficial in psychiatric conditions, including schizophrenia. Patients with schizophrenia exhibit mesolimbic dopamine hyperfunction consequent to an endogenous sensitization process. This ... -
Effects of N-acetylcysteine on spinal cord oxidative stress biomarkers in rats with neuropathic pain
(2017) [Artigo de periódico]N-acetylcysteine (NAC) inhibits nociceptive transmission. This effect has been associated partly with its antioxidant properties. However, the effect of NAC on the levels of lipid hydroperoxides (a pro-oxidant marker), ... -
N-acetylcysteine downregulates phosphorylated p-38 expression but does not reverse the increased superoxide anion levels in the spinal cord of rats with neuropathic pain
(2017) [Artigo de periódico]We determined the effect of N-acetylcysteine (NAC) on the expression of the phosphorylated p38 (p-p38) protein and superoxide anion generation (SAG), two important players in the processing of neuropathic pain, in the ... -
N-Acetylcysteine micronization by the seds technique using supercritical CO2
(2018) [Artigo de periódico]Abstract - N-Acetylcysteine (NAC) is a thiol (-SH) with a strong antioxidant activity. This compound has demonstrated positive effects on chronic kidney disease, cancer, pulmonary insufficiency and other diseases. The aim ... -
N-acetylcysteine protects against motor, optomotor and morphological deficits induced by 6-OHDA in zebrafish larvae
(2018) [Artigo de periódico]Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder. In addition to its highly debilitating motor symptoms, non-motor symptoms may precede their motor counterparts by many years, which ... -
Protective effect of N-acetyl-L-cysteine and rosuvastatin against oxidative stress in fibroblasts from asymptomatic patients with X-ALD : a preliminary study
(2021) [Artigo de periódico]Introduction: Several studies in the literature have evaluated the role of oxidative stress and adjuvant therapies for X-linked adrenoleukodystrophy (X-ALD). Here, we investigated whether n-acetyl-L-cysteine (NAC) and ...