Navegação Ciências Biológicas por Autor "Wyse, Angela Terezinha de Souza"

Resultados 1-16 de 16

    • Antioxidant effect of simvastatin throught oxidative imbalance caused by lisdexamfetamine dimesylate 

      Eger, Guilherme André; Ferreira, Vinicius Vialle; Batista, Camila Ribeiro; Bonde, Henrique; Lima, Daniela Delwing de; Wyse, Angela Terezinha de Souza; Cruz, Júlia Niehues da; Rodrigues, André Felipe; Delwing, Débora; Cruz, José Geraldo Pereira da (2016) [Artigo de periódico]
      The present study aims to directly investigate the behavioral and antioxidant effects of simvastatin in a model of bipolar mania induced by lisdexamfetamine dimesylate. Wistar rats were treated for 30 days with simvastatin. ...

    • Brain ischemia alters platelet ATP disphosphohydrolase and 5'-nucleotidase activities in naive and preconditioned rats 

      Frasseto, Silvana Soriano; Schetinger, Maria Rosa Chitolina; Schierholt, Rejane Cristina; Webber, Analupe; Bonan, Carla Denise; Wyse, Angela Terezinha de Souza; Dias, Renato Dutra; Netto, Carlos Alexandre; Sarkis, João José Freitas (2000) [Artigo de periódico]
      The effects of transient forebrain ischemia, reperfusion and ischemic preconditioning on rat blood platelet ATP diphosphohydrolase and 5'- nucleotidase activities were evaluated. Adult Wistar rats were submitted to 2 or ...

    • Chronic postnatal administration of methylmalonic acid provokes a decrease of myelin content and ganglioside N-acetylneuramic acid concentration in cerebrum of young rats 

      Brusque, Ana Maria; Rotta, Liane Nanci; Pettenuzzo, Letícia Ferreira; Junqueira, Debora; Schwarzbold, Carolina Vargas; Wyse, Angela Terezinha de Souza; Wannmacher, Clovis Milton Duval; Dutra Filho, Carlos Severo; Wajner, Moacir (2001) [Artigo de periódico]
      Levels of methylmalonic acid (MMA) comparable to those of human methylmalonic acidemia were achieved in blood (2-2.5 mmol/l) and brain (1.35 µmol/g) of rats by administering buffered MMA, pH 7.4, subcutaneously twice a day ...

    • Conectando os programas de pós-graduação à sociedade : uma experiência que une laboratórios de pesquisa e educação básica 

      Wyse, Angela Terezinha de Souza (2019) [Artigo de periódico]
      O presente artigo objetiva relatar o processo de construção e de elaboração de conteúdos da disciplina intitulada “Conectando o PPG Bioquímica ao Ensino Básico: Dos Laboratórios à Escola”, promovida pelo PPG em Ciências ...

    • Differential macrophage activation alters the expression profile of NTPDase and Ecto-5´-nucleotidase 

      Zanin, Rafael Fernandes; Braganhol, Elizandra; Bergamin, Letícia Scussel; Campesato, Luis Felipe Ingrassia; Zanotto Filho, Alfeu; Moreira, Jose Claudio Fonseca; Morrone, Fernanda Bueno; Sevigny, Jean; Schetinger, Maria Rosa Chitolina; Wyse, Angela Terezinha de Souza; Battastini, Ana Maria Oliveira (2012) [Artigo de periódico]
      Macrophages are key elements in the inflammatory process, whereas depending on the micro-environmental stimulation they exhibit a pro-inflammatory (classical/M1) or an anti-inflammatory/reparatory (alternative/M2) phenotype. ...

    • DNA damage in homocystinuria : 8-oxo-, 8-dihydro-2’-deoxyguanosine levels in cystathionine-β-synthase deficient patients and the in vitro protective effect of N-acetyl-L-cysteine 

      Vanzin, Camila Simioni; Mescka, Caroline Paula; Marchetti, Desirèe Padilha; Donida, Bruna; Deon, Marion; Jacques, Carlos Eduardo Diaz; Hauschild, Tatiane Cristina; Faverzani, Jéssica Lamberty; Hauschild, Tatiane Cristina; Moura, Dinara Jaqueline; Saffi, Jenifer; Coelho, Daniella de Moura; Wajner, Moacir; Wyse, Angela Terezinha de Souza; Vargas, Carmen Regla (2018) [Artigo de periódico]
      Introduction: Homocysteine (Hcy) tissue accumulation occurs in a metabolic disease characterized biochemically by cystathionine β-synthase (CBS) deficiency and clinically by mental retardation, vascular problems, and ...

    • Effect of sciatic nerve transection on acetylcholinesterase activity in spinal cord and skeletal muscles of the bullfrog Lithobates catesbeianus 

      Kroth, Adarly; Mackedanz, Vanize; Matté, Cristiane; Wyse, Angela Terezinha de Souza; Ribeiro, Maria Flavia Marques; Partata, Wania Aparecida (2018) [Artigo de periódico]
      Sciatic nerve transection (SNT), a model for studying neuropathic pain, mimics the clinical symptoms of “phantom limb”, a pain condition that arises in humans after amputation or transverse spinal lesions. In some vertebrate ...

    • Effects of vitamin D administration on nociception and spinal cord pro-oxidant and antioxidant markers in a rat model of neuropathic pain 

      Santos, Maria do Carmo Quevedo; Silva, Thaisla Cristiane Borella da; Silva, Francielle Braz Oliveira da; Siebert, Cassiana; Kroth, Adarly; Silveira, Elza Maria Santos da; Wyse, Angela Terezinha de Souza; Partata, Wania Aparecida (2021) [Artigo de periódico]
      Reactive oxygen species (ROS) are involved in neuropathic pain, a complicated condition after nerve tissue lesion. Vitamin D appears to improve symptoms of pain and exhibits antioxidant properties. We investigated the ...

    • Evaluation of Na+, K+-ATPase activity in the brain of young rats after acute administration of fenproporex 

      Rezin, Gislaine Tezza; Scaini, Giselli; Gonçalves, Cinara L.; Ferreira, Gabriela K.; Cardoso, Mariane Ribeiro; Ferreira, Andréa Gisiane Kurek; Cunha, Maira Jaqueline da; Schmitz, Felipe; Varela, Roger Bitencourt; Quevedo, João Luciano de; Wyse, Angela Terezinha de Souza; Streck, Emilio Luiz (2014) [Artigo de periódico]
      Objectives: Fenproporex is an amphetamine-based anorectic which is rapidly converted into amphetamine in vivo. Na+, K+-ATPase is a membrane-bound enzyme necessary to maintain neuronal excitability. Considering that the ...

    • Expression of matrix metalloproteinases in patients with bipolar disorder 

      Chiarani, Fabria; Fries, Gabriel Rodrigo; Stertz, Laura; Ceresér, Keila Maria Mendes; Wyse, Angela Terezinha de Souza; Kapczinski, Flávio Pereira; Kunz, Maurício (2013) [Artigo de periódico]
      Objective: High cardiovascular mortality rates have been reported in patients with bipolar disorder (BD). Studies indicate that matrix metalloproteinases (MMPs) are implicated in cardiovascular diseases. We evaluated the ...

    • Homocysteine and other markers of cardiovascular risk during a manic episode in patients with bipolar disorder 

      Chiarani, Fabria; Tramontina, Juliana Fernandes; Ceresér, Keila Maria Mendes; Kunz, Maurício; Paim, Leonardo Ludwig; Vargas, Carmen Regla; Sitta, Angela; Machado, Sérgio Carlos Eduardo Pinto; Wyse, Angela Terezinha de Souza; Kapczinski, Flávio Pereira (2013) [Artigo de periódico]
      Objective: To evaluate serum levels of different biomarkers associated with cardiovascular disease in patients with bipolar disorder (BD). Patients were prospectively evaluated in two separate instances: during acute mania ...

    • Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain 

      Silva, Alexandre Rodrigues da; Ruschel, Cristiano; Helegda, Celio; Wyse, Angela Terezinha de Souza; Wannmacher, Clovis Milton Duval; Wajner, Moacir; Dutra Filho, Carlos Severo (2001) [Artigo de periódico]
      2-Hydroxybutyric acid appears at high concentrations in situations related to deficient energy metabolism (e.g., birth asphyxia) and also in inherited metabolic diseases affecting the central nervous system during neonatal ...

    • In vivo and in vitro effect of imipramine and fluoxetine on Na+, K+-ATPase activity in synaptic plasma membranes from the cerebral cortex of rats 

      Zanatta, Lino Marcos; Nascimento, Fernanda Costa do; Barros, Sonja Verginia Tamborena; Silva, Georgia Regina S. da; Zugno, Alexandra Ioppi; Netto, Carlos Alexandre; Wyse, Angela Terezinha de Souza (2001) [Artigo de periódico]
      The effects of in vivo chronic treatment and in vitro addition of imipramine, a tricyclic antidepressant, or fluoxetine, a selective serotonin reuptake inhibitor, on the cortical membrane-bound Na+,K+- ATPase activity were ...

    • P2X7 receptor contributes to long-term neuroinflammation and cognitive impairment in sepsis-surviving mice 

      Alves, Vinícius Santos; Silva, Joyce Pereira da; Rodrigues, Fabiana Cristina; Araújo, Suzana Maria Bernardino; Souza, André Luiz Gouvêa de; Aguiar, Raíssa Leite Tenorio; Santos, Stephanie Alexia Cristina Silva; Silva, Milla Souza Pessoa da; Ferreira, Fernanda Silva; Marques, Eduardo Peil; Passos, Beatriz Amanda Barbosa Rangel dos; Gutierrez, Tatiana Maron; Kurtenbach, Eleonora; Costa, Robson da; Figueiredo, Claudia Pinto; Wyse, Angela Terezinha de Souza; Silva, Robson Coutinho; Savio, Luiz Eduardo Baggio (2023) [Artigo de periódico]
      Introduction: sepsis is defined as a multifactorial debilitating condition with high risks of death. The intense inflammatory response causes deleterious effects on the brain, a condition called sepsis-associated encephalopathy. ...

    • Purinergic signaling in the modulation of redox biology 

      Savio, Luiz Eduardo Baggio; Aguiar, Raíssa Leite Tenorio; Alves, Vinícius Santos; Silva, Robson Coutinho; Wyse, Angela Terezinha de Souza (2021) [Artigo de periódico]
      Purinergic signaling is a cell communication pathway mediated by extracellular nucleotides and nucleosides. Tri- and diphosphonucleotides are released in physiological and pathological circumstances activating purinergic ...

    • Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from streptozotocin-induced diabetic rats 

      Kolling, Jenifer; Kolling, Janaína; Franceschi, Itiane Diehl de; Nishihira, Vivian Shinobu Kishimoto; Baldissera, Matheus Dellaméa; Pinto, Claudia Grigolo; Mezzomo, Nathana Jamille; Carmo, Guilherme Machado do; Feksa, Luciane Rosa; Fernandes, Liana da Silva; Oliveira, Gilberto Orengo de; Vaucher, Rodrigo de Almeida; Giongo, Janice Luehring; Wyse, Angela Terezinha de Souza; Wannmacher, Clovis Milton Duval; Rech, Virgínia Cielo (2019) [Artigo de periódico]
      Type 1 diabetes (T1D) is the result of the selective destruction of the pancreatic β-cells by T cells of the immune system. Although spleen is a secondary lymphoid organ, it is also involved in the T1D pathogenesis. However, ...