Navegação Ciências Biológicas por Autor "Gaelzer, Mariana Maier"

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    • Phosphatidylinositol 3-kinase/AKT pathway inhibition by doxazosin promotes glioblastoma cells death, upregulation of p53 and triggers low neurotoxicity 

      Gaelzer, Mariana Maier; Coelho, Bárbara Paranhos; Quadros, Alice Hoffmann de; Hoppe, Juliana Bender; Terra, Silvia Resende; Guerra, Maria Cristina Azambuja Barea da Silveira; Usach, Vanina; Guma, Fátima Theresinha Costa Rodrigues; Goncalves, Carlos Alberto Saraiva; Setton-Avruj, Patricia Clara; Battastini, Ana Maria Oliveira; Salbego, Christianne Gazzana (2016) [Artigo de periódico]
      Glioblastoma is the most frequent and malignant brain tumor. Treatment includes chemotherapy with temozolomide concomitant with surgical resection and/or irradiation. However, a number of cases are resistant to temozolomide, ...