Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
dc.contributor.advisor | Gnoatto, Simone Cristina Baggio | pt_BR |
dc.contributor.author | Santos, Eduardo da Silveira dos | pt_BR |
dc.date.accessioned | 2018-11-17T03:12:08Z | pt_BR |
dc.date.issued | 2016 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/184776 | pt_BR |
dc.description.abstract | A new series of 4-methyl-quinolines was synthesized as potential cruzain inhibitors using Doebner-Von Miller synthesis. The compounds (1a-f) are undergoing analysis in order to guarantee their purities and further explore their biological activity. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.rights | Open Access | en |
dc.subject | Quinoline | en |
dc.subject | Farmácia | pt_BR |
dc.subject | Doebner-Von Miller | en |
dc.subject | Cruzain | en |
dc.subject | Trypanosoma cruzi | en |
dc.subject | Chagas disease | en |
dc.title | Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity | pt_BR |
dc.type | Trabalho de conclusão de graduação | pt_BR |
dc.identifier.nrb | 001020636 | pt_BR |
dc.degree.grantor | Universidade Federal do Rio Grande do Sul | pt_BR |
dc.degree.department | Faculdade de Farmácia | pt_BR |
dc.degree.local | Porto Alegre, BR-RS | pt_BR |
dc.degree.date | 2016 | pt_BR |
dc.degree.graduation | Farmácia | pt_BR |
dc.degree.level | graduação | pt_BR |
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