Browsing by Subject "Insuficiência ovariana primária"
Now showing items 1-5 of 5
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Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression
(2022) [Journal article]Background: The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells. Fragile X mental retardation 1 ... -
FMR1 and AKT/mTOR signaling in human granulosa cells : functional interaction and impact on ovarian response
(2021) [Journal article]We aimed to determine whether a functional link with impact on female ovarian reserve exists between FMR1 expression and expression ratios of AKT/mTOR signaling genes in human granulosa cells in vivo, as suggested from ... -
FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve
(2018) [Journal article]Background: Fragile-X-Mental-Retardation-1- (FMR1)-gene is supposed to be a key gene for ovarian reserve and folliculogenesis. It contains in its 5’-UTR a triplet-base-repeat (CGG), that varies between 26 and 34 in general ... -
Insuficiência ovariana precoce : alternativas para manutenção da fertilidade
(2022) [Book chapter] -
Women with primary ovarian insufficiency have lower bone mineral density
(2011) [Journal article]The aim of the present study was to assess the prevalence of osteoporosis in a sample of 32 patients with spontaneous primary ovarian insufficiency (POI) in comparison to reference groups of 25 pre- and 55 postmenopausal ...
