Navegação por Autor "Strowitzki, Thomas"
Resultados 1-5 de 5
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Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression
(2022) [Artigo de periódico]Background: The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells. Fragile X mental retardation 1 ... -
Factors influencing success rate of intracytoplasmic sperm injection with azoospermic male patients
(2020) [Artigo de periódico]Introduction Azoospermia affects about 1% of men, of whom up to 15% inquire about infertility treatment. Information about predictive factors for these couples is very limited. Patients, Materials and Methods We performed ... -
FMR1 and AKT/mTOR signaling in human granulosa cells : functional interaction and impact on ovarian response
(2021) [Artigo de periódico]We aimed to determine whether a functional link with impact on female ovarian reserve exists between FMR1 expression and expression ratios of AKT/mTOR signaling genes in human granulosa cells in vivo, as suggested from ... -
FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve
(2018) [Artigo de periódico]Background: Fragile-X-Mental-Retardation-1- (FMR1)-gene is supposed to be a key gene for ovarian reserve and folliculogenesis. It contains in its 5’-UTR a triplet-base-repeat (CGG), that varies between 26 and 34 in general ... -
Proliferation and metastatic potential of endometrial cancer cells in response to metformin treatment in a high versus normal glucose environment
(2016) [Artigo de periódico]In order to improve our understanding of the potential preventive and therapeutic role of metformin, the present study aimed to investigate the capability of low-dose metformin in the efficient inhibition of cancer development ...
