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dc.contributor.authorZembrzuski, Verônica Marquespt_BR
dc.contributor.authorCallegari-Jacques, Sidia Mariapt_BR
dc.contributor.authorHutz, Mara Helenapt_BR
dc.date.accessioned2011-01-15T05:58:59Zpt_BR
dc.date.issued2006pt_BR
dc.identifier.issn0003-4800pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/27437pt_BR
dc.description.abstractTen ancestry informative markers were investigated in 101 coronary artery disease patients and 102 healthy controls from a Southern Brazilian population, in order to determine if stratification occurs in this population. The degree of African admixture detected in this population was estimated to be as high as 6%, but no differences between cases and controls were observed. Using an African Ancestry Index (AAI) that estimates admixture at the individual level it was possible to remove from the samples those individuals with evidence of African admixture. Therefore we have shown that it is possible to control for population stratification by choosing individuals, without the loss of statistical power that occurs with the use of other methods of genomic control.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofAnnals of human genetics. London. Vol. 70, no. 6 (Nov. 2006), p. 822-828pt_BR
dc.rightsOpen Accessen
dc.subjectEstatística aplicada : Ciências humanaspt_BR
dc.subjectGenética de populaçõespt_BR
dc.titleApplication of an African Ancestry Index as a genomic control approach in a brazilian populationpt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000573876pt_BR
dc.type.originEstrangeiropt_BR


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