Navegação Ciências Exatas e da Terra por Autor "Silveira, Gustavo Pozza"
Resultados 1-8 de 8
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Arginylglycylaspartic Acid-Surface-Functionalized Doxorubicin-Loaded Lipid-Core nanocapsules as a strategy to target Alpha(V) Beta(3) integrin expressed on tumor cells
Antonow, Michelli Barcelos; Franco, Camila; Prado, Willian Andrade; Beckenkamp, Aline; Silveira, Gustavo Pozza; Buffon, Andreia; Guterres, Silvia Stanisçuaski; Pohlmann, Adriana Raffin (2018) [Artigo de periódico]Doxorubicin (Dox) clinical use is limited by dose-related cardiomyopathy, becoming more prevalent with increasing cumulative doses. Previously, we developed Dox-loaded lipid-core nanocapsules (Dox-LNC) and, in this study, ... -
Crystal structure and absolute configuration of (3aR,30aR,7aS,70aS)-2,2,20,20-tetramethyl- 3a,6,7,7a,30a,60,70,70a-octahydro-4,40-bi[1,3- benzodioxolyl], obtained from a Pd-catalyzed homocoupling reaction
Macias Lopez, Mario Alberto; Pandolfi Graziosi, Enrique; Schapiro Ferrara, Valeria; Silveira, Gustavo Pozza; Vilela, Guilherme Drechsler; Suescun Pereyra, Leopoldo (2017) [Artigo de periódico]The absolute configuration, i.e. (3aR,30aR,7aS,70aS), of the title compound, C18H26O4, synthesized via a palladium-catalyzed homocoupling reaction, was determined on the basis of the synthetic pathway and was confirmed by ... -
Crystal structure of 4-methyl-N-{(E)- methyl[(3aR,8aS)-2-oxo-3,3a,8,8a-tetrahydro- 2H-indeno[1,2-d][1,3]oxazol-3- yl]-λ4-sulfanylidene}benzenesulfonamide
Pereira, Patrícia Abreu; Noll, Bruce C.; Oliver, Allen G.; Silveira, Gustavo Pozza (2015) [Artigo de periódico]The formulation that the title compound, C18H18N2O4S2, adopts is a zwitterionic core with the charge separated to the sulfilimine S and N atoms and is supported by the two different S—N bond distances about the sulfinimine ... -
Crystal structure of (4R,5S)-4-methyl-3-methylsulfinyl-5-phenyl-1,3-oxazolidin-2-one
Silveira, Gustavo Pozza; Silva, Vinícius Flores da; Oliver, Allen G. (2014) [Artigo de periódico]The absolute structure of the chiral asymmetric indole precursor title compound, C11H13NO3S, was confirmed by refinement of the Flack and Hooft parameters and is that expected based on the starting materials for the ... -
Crystal structure of 5-O-benzoyl-2,3-O-isopropylidene- D-ribono-1,4-lactone
Bortoluzzi, Adailton João; Silveira, Gustavo Pozza; Sá, Marcus Mandolesi (2017) [Artigo de periódico]In the title compound, C15H16O6, obtained from the acylation reaction between 2,3-O-isopropylidene-d-ribono-1,4-lactone and benzoyl chloride, the known absolute configuration for the lactone moiety of the ester substituent ... -
Molecular sieves mediated green per-O-acetylation of carbohydrate templates and lipase catalyzed regioselective alcoholysis of 2,3,5-tri-O-acetyl-D-ribonolactone
Cardozo, Herbert Martins; Ribeiro, Thaís de Freitas; Sá, Marcus Mandolesi; Sebrão, Damianni; Nascimento, Maria da Graça; Silveira, Gustavo Pozza (2015) [Artigo de periódico]The per-O-acetylation of D-ribono-1,4-lactone and representative carbohydrates through the combination of acetic anhydride and molecular sieves under solvent-free conditions is demonstrated. The use of 13X/KCl molecular ... -
Nanoemulsion improves the antifungal activity of allylic thiocyanates against yeasts and filamentous pathogenic fungi
Dalla Lana, Daiane Flores; Giuliani, Laura Minussi; Reoleon, Jéssica Brandão; Lopes, William; Vainstein, Marilene Henning; Danielli, Letícia Jacobi; Bergamo, Vanessa Zafaneli; Pippi, Bruna; Appel, Miriam Angela Marchi; Teixeira, Mário Lettieri; Oliveira, Luis Flávio Souza de; Machado, Michel Mansur; Andrade, Saulo Fernandes de; Sá, Marcus Mandolesi; Ferreira, Misael; Munaretto, Laiéli dos Santos; Cruz, Letícia; Silveira, Gustavo Pozza; Silva, Edilma Elayne da; Fuentefria, Alexandre Meneghello (2018) [Artigo de periódico]We report the antifungal and antichemotactic activities of a series of allylic thiocyanates with low toxicity. We also show improved antifungal activity of the most promising compound when used in a nanoemulsion (NE). The ... -
(R)-4-Isopropyl-3-isopropylsulfanyl-5,5-diphenyl-1,3-oxazolidin-2-one
Silveira, Gustavo Pozza; Carvalho, Cassandra Bonfante de; Oliver, Allen G. (2012) [Artigo de periódico]The title compound, C21H25NO2S, consists of a five-membered heterocyclic ring, with pendant phenyl groups, an isopropyl group and a thioether residue. The thioether bonds to the heterocycle via the N atom. The absolute ...