Browsing Exact and Earth Sciences by Author "Goldim, José Roberto"

Now showing items 1-2 of 2

    • Pediatric cancer and Li-Fraumeni/Li-Fraumeni-like syndromes : a review for the pediatrician 

      Rossi, Cristina; Giacomazzi, Juliana; Netto, Cristina Brinckmann Oliveira; Santos-Silva, Patrícia; Selistre, Simone Geiger de Almeida; Maia, Ana Luiza Silva; Oliveira, Viviane Ziebell de; Camey, Suzi Alves; Goldim, José Roberto; Prolla, Patrícia Ashton (2015) [Journal article]
      Introduction: cancer is the second leading cause of death in children between the ages of 0 and 14 years, corresponding to approximately 3% of all cases diagnosed in Brazil. A significant percentage (5-10%) of pediatric ...

    • Prevalence of the TP53 p.R337H mutation in breast cancer patients in Brazil 

      Giacomazzi, Juliana; Graudenz, Márcia Silveira; Osório, Cynthia Aparecida Bueno de Toledo; Santos, Patrícia Koehler dos; Palmero, Edenir Inêz; Oliveira, Marcelo Zagonel de; Michelli, Rodrigo Augusto Depieri; Scapulatempo Neto, Cristovam; Fernandes, Gabriela de Carvalho; Achatz, Maria Isabel Alves de Souza Waddington; Martel-Planche, Ghyslaine; Soares, Fernando A.; Caleffi, Maira; Goldim, José Roberto; Hainaut, Pierre; Camey, Suzi Alves; Prolla, Patrícia Ashton (2014) [Journal article]
      Germline TP53 mutations predispose individuals to multiple cancers and are associated with Li-Fraumeni/Li-Fraumeni-Like Syndromes (LFS/LFL). The founder mutation TP53 p.R337H is detected in 0.3% of the general population ...