Navegação Ciências Exatas e da Terra por Autor "Castro, Mauro Antônio Alves"
Resultados 1-4 de 4
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Evolutionary origins of human apoptosis and genome-stability gene networks
(2008) [Artigo de periódico]Apoptosis is essential for complex multicellular organisms and its failure is associated with genome instability and cancer. Interactions between apoptosis and genome-maintenance mechanisms have been extensively documented ... -
Evolutionary plasticity determination by orthologous groups distribution
(2011) [Artigo de periódico]Background: Genetic plasticity may be understood as the ability of a functional gene network to tolerate alterations in its components or structure. Usually, the studies involving gene modifications in the course of the ... -
Impaired expression of NER gene network in sporadic solid tumors
(2007) [Artigo de periódico]Nucleotide repair genes are not generally altered in sporadic solid tumors. However, point mutations are found scattered throughout the genome of cancer cells indicating that the repair pathways are dysfunctional. To address ... -
Preferential duplication of intermodular hub genes : an evolutionary signature in eukaryotes genome networks
(2013) [Artigo de periódico]Whole genome protein-protein association networks are not random and their topological properties stem from genome evolution mechanisms. In fact, more connected, but less clustered proteins are related to genes that, in ...
