Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle=Tumor maligno da bainha de nervo periférico como causa de insuficiência cardíaca crônica em bovinos
dc.contributor.author | Pavarini, Saulo Petinatti | pt_BR |
dc.contributor.author | Gomes, Danilo Carloto | pt_BR |
dc.contributor.author | Bandinelli, Marcele Bettim | pt_BR |
dc.contributor.author | Wouters, Flademir | pt_BR |
dc.contributor.author | Sonne, Luciana | pt_BR |
dc.contributor.author | Driemeier, David | pt_BR |
dc.contributor.author | Cruz, Claudio Estevao Farias da | pt_BR |
dc.date.accessioned | 2015-02-12T02:15:36Z | pt_BR |
dc.date.issued | 2013 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/110053 | pt_BR |
dc.description.abstract | Chronic cardiac insufficiency was associated with a malignant peripheral nerve sheath tumor in a cow. An eight-year-old cow developed a progressive condition (over a period of three months) characterized by an enhanced abdominal volume, reluctance to move, a positive jugular pulse, watery diarrhea and death. At necropsy, moderate subcutaneous edema and an enhanced hepatic lobular pattern were observed. A 23x20x11 cm firm, grayish-white mass adhered to and infiltrated the right atrium. Multiple firm, yellowish-white nodules of 0.5 to 12 cm in diameter were diffusely scattered in the epicardium and parietal pericardium. Histologically, the tumor was poorly circumscribed with foci of infiltration of the myocardium. The neoplastic cells had two major histologic patterns, Antoni types A and B. Within occasional foci, pleomorphic cells with an epithelioid appearance were present in addition to multinucleated cells with periodic acid Schiff (PAS)-positive cytoplasmic globules. Foci of cartilaginous and granular differentiations were interspersed among the neoplastic cells. Multiple vessels presented wall hyalinization and tumoral embolus. Large necrotic foci with mineralization and cholesterol clefts were also observed. Immunohistochemically, the tumor was positive for S100 protein, vimentin and neuron-specific enolase labeling. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Acta Veterinaria Scandinavica. Cambridge: BioMed Central, 2013. Vol. 55, n.7(jan. 2013), [6f], Relato de Caso | pt_BR |
dc.rights | Open Access | en |
dc.subject | Tumores malignos | pt_BR |
dc.subject | Cattle | en |
dc.subject | Insuficiência cardíaca : Diagnóstico | pt_BR |
dc.subject | Immunohistochemical procedures | en |
dc.subject | Imunoistoquímica | pt_BR |
dc.subject | Neoplasm | en |
dc.subject | Malignant schwannoma | en |
dc.title | Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle=Tumor maligno da bainha de nervo periférico como causa de insuficiência cardíaca crônica em bovinos | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 000907049 | pt_BR |
dc.type.origin | Estrangeiro | pt_BR |
Este item está licenciado na Creative Commons License
-
Artigos de Periódicos (39774)Ciências Agrárias (3946)