Navegação por Assunto "Genomics"
Resultados 1-7 de 7
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Challenges and recommendations to increasing the use of exome sequencing and whole genome sequencing for diagnosing rare diseases in Brazil : an expert perspective
(2023) [Artigo de periódico]Early diagnosis of genetic rare diseases is an unmet need in Brazil, where an estimated 10-13 million people live with these conditions. Increased use of chromosome microarray assays, exome sequencing, and whole genome ... -
Comparative genomics supports that brazilian bioethanol Saccharomyces cerevisiae comprise a unified group of domesticated strains related to cachaça spirit yeasts
(2021) [Artigo de periódico]Ethanol production from sugarcane is a key renewable fuel industry in Brazil. Major drivers of this alcoholic fermentation are Saccharomyces cerevisiae strains that originally were contaminants to the system and yet prevail ... -
Genetic basis of reproductive performance and antibody response in pigs during a porcine reproductive and respiratory syndrome outbreak
(2020) [Dissertação]Total antibody response, measured as sample-to-positive ratio (S/P ratio), has been proposed as an indicator trait to improve reproductive performance in pigs infected with the porcine reproductive and respiratory syndrome ... -
Genome characterization of the first mimiviruses of lineage C isolated in Brazil
(2017) [Artigo de periódico]The family Mimiviridae, comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba polyphaga mimivirus (APMV), in 2003. In this work, we describe the genome analysis of two new ... -
Holobionts and their hologenomes: evolution with mixed modes of inheritance
(2018) [Artigo de periódico]Symbioses are ubiquitous and have played an influential role in the evolution of life on Earth. Genomic studies are now revealing a huge diversity of associations among hosts and their microbiotas, allowing us to characterize ... -
Opportunities and challenges for newborn screening and early diagnosis of rare diseases in Latin America
(2022) [Artigo de periódico]Rare diseases (RDs) cause considerable death and disability in Latin America. Still, there is no consensus on their definition across the region. Patients with RDs face a diagnostic odyssey to find a correct diagnosis, ... -
A study on graph neural networks for classification tasks and model interpretability on genomic datasets
(2024) [Trabalho de conclusão de graduação]Recently, a few works have started proposing the use of graph neural networks (GNNs) to embed knowledge of gene interactions in machine learning models and thus produce more robust classifiers for genomic classification ...