Browsing by Subject "Fenótipo secretor associado à senescência"

Now showing items 1-1 of 1

    • Obesity drives adipose-derived stem cells into a senescent and dysfunctional phenotype associated with P38MAPK/NF-KB axis 

      Grun, Lucas Kich; Maurmann, Rafael Moura; Scholl, Juliete Nathali; Fogaça, M. E.; Schmitz, Carine Raquel Richter; Dias, Camila kehl; Gasparotto, Juciano; Padoin, Alexandre Vontobel; Mottin, Cláudio Corá; Klamt, Fabio; Figueiró, Fabrício; Jones, Marcus Herbert; Chiela, Eduardo Cremonese Filippi; Guma, Fátima Theresinha Costa Rodrigues; Barbé-Tuana, Florencia María (2023) [Journal article]
      Background: Adipose-derived stem cells (ADSC) are multipotent cells implicated in tissue homeostasis. Obesity represents a chronic inflammatory disease associated with metabolic dysfunction and age-related mechanisms, with ...