Navegação por Assunto "ERK"

Resultados 1-2 de 2

    • Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation 

      Pillat, Micheli Mainardi; Lameu, Claudiana; Trujillo, Cleber A.; Glaser, Talita; Cappellari, Angélica Regina; Negraes, Priscilla D.; Battastini, Ana Maria Oliveira; Schwindt, Telma T.; Muotri, Alysson Renato; Ulrich, Henning (2016) [Artigo de periódico]
      During brain development, cells proliferate, migrate and differentiate in highly accurate patterns. In this context, published results indicate that bradykinin functions in neural fate determination, favoring neurogenesis ...

    • Extracellular HSP70 activates ERK1/2, NF-kB and pro-inflammatory gene transcription through binding with RAGE in A549 human lung cancer cells 

      Somensi, Nauana; Brum, Pedro Ozorio; Ramos, Vitor de Miranda; Gasparotto, Juciano; Zanotto Filho, Alfeu; Rostirolla, Diana Carolina; Morrone, Maurilio da Silva; Moreira, Jose Claudio Fonseca; Gelain, Daniel Pens (2017) [Artigo de periódico]
      Background/Aims: Heat shock protein 70 (HSP70) has been recently described with extracellular actions, where it is actively released in inflammatory conditions. Acting as DAMPs (damage associated molecular pattern) , ...