• Admixture in Latin America : geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals 

      Ruiz-Linares, Andres; Adhikari, Kaustubh; Acunã Alonzo, Víctor; Quinto Sanchez, Mirsha; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Everardo, Paola; Avila, Francisco de; Gómez Valdés, Jorge A.; León Mimila, Paola; Hunemeier, Tábita; Ramallo, Virgínia; Cerqueira, Caio Cesar Silva de; Burley, Mari-Wyn; Konca, Esra; Oliveira, Marcelo Zagonel de; Veronez, Maurício Roberto; Rubio Codina, Marta; Attanasio, Orazio; Gibbon, Sahra; Ray, Nicolas; Gallo, Carla; Poletti, Giovanni; Rosique, Javier; Faccini, Lavinia Schuler; Salzano, Francisco Mauro; Bortolini, Maria Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; Balding, David; González-José, Rolando (2014) [Artigo de periódico]
    • Automatic landmarking identifies new loci associated with face morphology and implicates Neanderthal introgression in human nasal shape 

      Li, Qing; Chen, Yingjie; Faux, Pierre; Delgado, Miguel Eduardo; Hurtado, Malena; Fuentes Guajardo, Macarena; Hurtado, Malena; Villegas, Valeria; Ramallo, Virgínia; Giardina, Andrea; Bortolini, Maria Cátira; Adhikari, Kaustubh; Ruiz-Linares, Andres (2022) [Artigo de periódico]
      We report a genome-wide association study of facial features in >6000 Latin Americans based on automatic landmarking of 2D portraits and testing for association with inter-landmark distances. We detected significant ...
    • A bayesian approach to genome/linguistic relationships in native south americans 

      Amorim, Carlos Eduardo Guerra; Machado, Rafael Bisso; Ramallo, Virgínia; Bortolini, Maria Cátira; Bonatto, Sandro Luis; Salzano, Francisco Mauro; Hunemeier, Tábita (2013) [Artigo de periódico]
      The relationship between the evolution of genes and languages has been studied for over three decades. These studies rely on the assumption that languages, as many other cultural traits, evolve in a gene-like manner, ...
    • Developmental pathways inferred from modularity, morphological integration and fluctuating asymmetry patterns in the human face 

      Quinto Sanchez, Mirsha; Muñoz-Muñoz, Francesc; Gómez Valdés, Jorge A.; Cintas, Célia; Navarro, Jose Pablo; Cerqueira, Caio Cesar Silva de; Paschetta, Carolina; Azevedo, Soledad de; Ramallo, Virgínia; Acunã Alonzo, Víctor; Adhikari, Kaustubh; Fuentes Guajardo, Macarena; Hunemeier, Tábita; Everardo, Paola; Avila, Francisco de; Jaramillo, Claudia; Arias, Williams; Gallo, Carla; Poletti, Giovanni; Bedoya, Gabriel; Bortolini, Maria Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Rosique, Javier; Ruiz-Linares, Andres; González-José, Rolando (2018) [Artigo de periódico]
      Facial asymmetries are usually measured and interpreted as proxies to developmental noise. However, analyses focused on its developmental and genetic architecture are scarce. To advance on this topic, studies based on a ...
    • Facial asymmetry and genetic ancestry in Latin American admixed populations 

      Quinto Sanchez, Mirsha; Adhikari, Kaustubh; Acunã Alonzo, Víctor; Cintas, Célia; Cerqueira, Caio Cesar Silva de; Ramallo, Virgínia; Castillo, Lucia; Farrera, Alodi; Jaramillo, Claudia; Arias, Williams; Fuentes, Macarena; Everardo, Paola; Avila, Francisco de; Gómez Valdés, Jorge A.; Hunemeier, Tábita; Gibbon, Sahra; Gallo, Carla; Poletti, Giovanni; Rosique, Javier; Bortolini, Maria Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; Ruiz-Linares, Andres; Gonzáles José, Rolando (2015) [Artigo de periódico]
      Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of ...
    • Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the Andes 

      Jacovas, Vanessa Cristina; Rovaris, Diego Luiz; Peréz, Orlando; Azevedo, Soledad de; Macedo, Gabriel Souza; Sandoval, José Raul; Salazar Granara, Alberto Alcibiades; Villena, Mercedes; Dugoujon, Jean-Michel; Machado, Rafael Bisso; Petzi-Erler, Maria Luiza; Salzano, Francisco Mauro; Prolla, Patrícia Ashton; Ramallo, Virgínia; Bortolini, Maria Cátira (2015) [Artigo de periódico]
      The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 individuals ...
    • A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation 

      Adhikari, Kaustubh; Fuentes Guajardo, Macarena; Quinto Sanchez, Mirsha; Mendoza Revilla, Javier; Chacón Duque, Juan Camilo; Acunã Alonzo, Víctor; Jaramillo, Claudia; Arias, William; Barquera Lozano, Rodrigo; Macín Pérez, Gastón; Gómez Valdés, Jorge A.; Villamil Ramírez, Hugo; Hunemeier, Tábita; Ramallo, Virgínia; Cerqueira, Caio Cesar Silva de; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Gallo, Carla; Poletti, Giovanni; Faccini, Lavinia Schuler; Salzano, Francisco Mauro; Bortolini, Maria Cátira; Canizales-Quinteros, Samuel; Cheeseman, Michael; Rosique, Javier; Bedoya, Gabriel; Rothhammer, Francisco; Headon, Denis; González-José, Rolando; Balding, David; Ruiz-Linares, Andres (2016) [Artigo de periódico]
      We report a genome-wide association scan for facial features in B6,000 Latin Americans. We evaluated 14 traits on an ordinal scale and found significant association (P valueso5 10 8) at single-nucleotide polymorphisms ...
    • Implications of the admixture process in skin color molecular assessment 

      Cerqueira, Caio Cesar Silva de; Hunemeier, Tábita; Gómez Valdés, Jorge A.; Ramallo, Virgínia; Krause, Carla Daiana Demkio Volasco; Barbosa, Ana Angélica Leal; Vargas Pinilla, Pedro; Dornelles, Rodrigo Ciconet; Longo, Dânae; Rothhammer, Francisco; Bedoya, Gabriel; Canizales-Quinteros, Samuel; Acunã Alonzo, Víctor; Gallo, Carla; Poletti, Giovanni; González-José, Rolando; Salzano, Francisco Mauro; Callegari-Jacques, Sidia Maria; Faccini, Lavinia Schuler; Ruiz-Linares, Andres; Bortolini, Maria Cátira; CANDELA - Consortium for the Analysis of the Diversity and Evolution of Latin America (2014) [Artigo de periódico]
      The understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes ...
    • Socioeconomic status is not related with facial fluctuating asymmetry : evidence from latin-american populations 

      Quinto Sanchez, Mirsha; Cintas, Célia; Cerqueira, Caio Cesar Silva de; Ramallo, Virgínia; Acunã Alonzo, Víctor; Adhikari, Kaustubh; Castillo, Lucia; Gómez Valdés, Jorge A.; Everardo, Paola; Avila, Francisco de; Hunemeier, Tábita; Jaramillo, Claudia; Arias, Williams; Fuentes, Macarena; Gallo, Carla; Poletti, Giovanni; Faccini, Lavinia Schuler; Bortolini, Maria Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; Rosique, Javier; Ruiz-Linares, Andres; González-José, Rolando (2017) [Artigo de periódico]
      The expression of facial asymmetries has been recurrently related with poverty and/or disadvantaged socioeconomic status. Departing from the developmental instability theory, previous approaches attempted to test the ...
    • The impact of socioeconomic and phenotypic traits on self-perception of ethnicity in Latin America 

      Paschetta, Carolina; Azevedo, Soledad de; Ramallo, Virgínia; Cintas, Célia; Peréz, Orlando; Pablo Navarro, Jose; Bandieri, Lucas; Quinto Sanchez, Mirsha; Adhikari, Kaustubh; Bortolini, Maria Cátira; Poletti, Giovanni; Gallo, Carla; Bedoya, Gabriel; Rothhammer, Francisco; Acunã Alonzo, Víctor; Ruiz-Linares, Andres; González-José, Rolando (2021) [Artigo de periódico]
      Self-perception of ethnicity is a complex social trait shaped by both, biological and non-biological factors. We developed a comprehensive analysis of ethnic self-perception (ESP) on a large sample of Latin American mestizos ...
    • Variações genéticas na via de TP53 em nativos americanos : sinais de adaptações ao clima 

      Jacovas, Vanessa Cristina (2015) [Dissertação]
      Considerando o papel fundamental da proteína p53 na homeostase celular, buscamos no presente trabalho correlacionar variações comuns em genes ligados a rede clássica de TP53 com variáveis ambientais e geográficas em distintas ...