Browsing by Author "Bingle, Lynne"

Now showing items 1-2 of 2

    • Drug-based therapy for advanced adenoid cystic carcinoma : current landscape and challenges based on an overview of registered clinical trials 

      Wagner, Vivian Petersen; Ferrarotto, Renata; Vargas, Pablo Agustin; Martins, Manoela Domingues; Bingle, Colin D.; Bingle, Lynne (2023) [Journal article]
      Adenoid cystic carcinoma (ACC) has a significant patient-population in need of effective systemic therapy, as no drug is currently approved by the FDA for its management. We critically reviewed ACC-clinical trials (CT) ...

    • TrkB-targeted therapy for mucoepidermoid carcinoma 

      Wagner, Vivian Petersen; Martins, Manoela Domingues; Amoura, Esra; Zanella, Virgilio Gonzales; Roesler, Rafael; De-Farias, Caroline Brunetto; Bingle, Colin D.; Vargas, Pablo Agustin; Bingle, Lynne (2020) [Journal article]
      The brain-derived neurotrophic factor (BDNF)/tyrosine receptor kinase B (TrkB) pathway was previously associated with key oncogenic outcomes in a number of adenocarcinomas. The aim of our study was to determine the role ...