Browsing by Author "Ulrich, Henning"

Now showing items 1-5 of 5

    • Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation 

      Pillat, Micheli Mainardi; Lameu, Claudiana; Trujillo, Cleber A.; Glaser, Talita; Cappellari, Angélica Regina; Negraes, Priscilla D.; Battastini, Ana Maria Oliveira; Schwindt, Telma T.; Muotri, Alysson Renato; Ulrich, Henning (2016) [Journal article]
      During brain development, cells proliferate, migrate and differentiate in highly accurate patterns. In this context, published results indicate that bradykinin functions in neural fate determination, favoring neurogenesis ...

    • Characterization of ectonucleotidases in human medulloblastoma cell lines : ecto-5´NT/CD73 in metastasis as potential prognostic factor 

      Cappellari, Angélica Regina; Rockenbach, Liliana; Dietrich, Fabrícia; Clarimundo, Vanessa Schuck; Glaser, Talita; Braganhol, Elizandra; Abujamra, Ana Lúcia; Roesler, Rafael; Ulrich, Henning; Battastini, Ana Maria Oliveira (2012) [Journal article]
      Medulloblastoma (MB) is the most common malignant brain tumor in children and occurs mainly in the cerebellum. Important intracellular signaling molecules, such those present in the Sonic Hedgehog and Wnt pathways, are ...

    • Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients 

      Pietrobon, Anna Julia; Andrejew, Roberta; Custódio, Ricardo Wesley Alberca; Oliveira, Luana de Mendonça; Scholl, Juliete Nathali; Teixeira, Franciane Mouradian Emidio; Brito, Cyro Alves de; Glaser, Talita; Kazmierski, Julia; Goffinet, Christine; Turdo, Anna Claudia; Yendo, Tatiana; Aoki, Valéria; Figueiró, Fabrício; Battastini, Ana Maria Oliveira; Ulrich, Henning; Benard, Gill; Duarte, Alberto Jose da Silva; Sato, Maria Notomi (2022) [Journal article]
      Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and adenosine (ADO) and might be involved in COVID-19 immunopathogenesis. Here, we explored the contribution of extracellular nucleotide ...

    • Ecto-5’-nucleotidase overexpression reduces tumor growth in a xenograph medulloblastoma model 

      Cappellari, Angélica Regina; Pillat, Micheli Mainardi; De Souza, Héllio Danny Nóbrega; Dietrich, Fabrícia; Oliveira, Francine Hehn de; Figueiró, Fabrício; Abujamra, Ana Lúcia; Roesler, Rafael; Lecka, Joanna; Sevigny, Jean; Battastini, Ana Maria Oliveira; Ulrich, Henning (2015) [Journal article]
      Background Ecto-5’-nucleotidase/CD73 (ecto-5’-NT) participates in extracellular ATP catabolism by converting adenosine monophosphate (AMP) into adenosine. This enzyme affects the progression and invasiveness of different ...

    • Exploring CD39 and CD73 expression as potential biomarkers in prostate cancer 

      Gardani, Carla Fernanda Furtado; Pedrazza, Eduardo Luiz; Paz, Victória Santos; Zanirati, Gabriele Goulart; Costa, Jaderson Costa da; Andrejew, Roberta; Ulrich, Henning; Scholl, Juliete Nathali; Figueiró, Fabrício; Rockenbach, Liliana; Morrone, Fernanda Bueno (2023) [Journal article]
      Prostate cancer (PC) is the most diagnosed tumor in males and ranks as the second leading cause of male mortality in the western world. The CD39 and CD73 enzymes play a crucial role in cancer regulation by degrading ...