Browsing by Author "Gillet, Reynald"
Now showing items 1-7 of 7
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Capsicumicine, a new bioinspired peptide from red peppers prevents staphylococcal biofilm in vitro and in vivo via a matrix anti-assembly mechanism of action
Von Borowski, Rafael Gomes; Chat, Sophie; Schneider, Rafael de Oliveira; Nonin-Lecomte, Sylvie; Bouaziz, Serge; Giudice, Emmanuel; Zimmer, Aline Rigon; Gnoatto, Simone Cristina Baggio; Macedo, Alexandre José; Gillet, Reynald (2021) [Journal article]Staphylococci are pathogenic biofilm-forming bacteria and a source of multidrug resistance and/or tolerance causing a broad spectrum of infections. These bacteria are enclosed in a matrix that allows them to colonize medical ... -
Obtenção de peptídeos e peptidomiméticos de Capsicum baccatum var. pendulum (Solanaceae) visando atividade antibiofilme
Von Borowski, Rafael Gomes (2019) [Thesis]O biofilme é uma matriz complexa, composta por comunidades de microrganismos envoltos em substâncias poliméricas extracelulares, aderidas a uma superfície biótica (tecidos e órgãos) ou abiótica (cateteres e próteses). O ... -
Promising antibiofilm activity of peptidomimetics
Von Borowski, Rafael Gomes; Gnoatto, Simone Cristina Baggio; Macedo, Alexandre José; Gillet, Reynald (2018) [Journal article]Pathogenic biofilms are a global health care concern, as they can cause extensive antibiotic resistance, morbidity, mortality, and thereby substantial economic loss. Scientific efforts have been made over the past few ... -
Pseudonajide peptide derived from snake venom alters cell envelope integrity interfering on biofilm formation in Staphylococcus epidermidis
Schneider, Rafael de Oliveira; Barros, Muriel Primon de; Von Borowski, Rafael Gomes; Chat, Sophie; Nonin-Lecomte, Sylvie; Gillet, Reynald; Macedo, Alexandre José (2020) [Journal article]Background: The increase in bacterial resistance phenotype cases is a global health problem. New strategies must be explored by the scientific community in order to create new treatment alternatives. Animal venoms are a ... -
Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation
Von Borowski, Rafael Gomes; Barros, Muriel Primon de; Silva, Denise Brentan; Lopes, Norberto Peporine; Zimmer, Karine Rigon; Staats, Charley Christian; Oliveira, Cristiane Bernardes de; Giudice, Emmanuel; Gillet, Reynald; Macedo, Alexandre José; Gnoatto, Simone Cristina Baggio; Zimmer, Aline Rigon (2020) [Journal article]Medical devices (indwelling) have greatly improved healthcare. Nevertheless, infections related to the use of these apparatuses continue to be a major clinical concern. Biofilms form on surfaces after bacterial adhesion, ... -
Trans-translation inhibition in ESKAPE bacteria and its perspectives as an antibiotic adjuvant
Silva, Rodrigo Campos da (2023) [Thesis]Hoje em dia estamos ameaçados sob o risco de voltar à era préantibiótica devido à disseminação da resistência antimicrobiana. O ressurgimento da morte por infecções, que eram consideradas facilmente tratáveis, exige a ... -
Trans-translation is an appealing target for the development of new antimicrobial compounds
Silva, Rodrigo Campos da; D'Urso, Gaetano; Delalande, Olivier; Giudice, Emmanuel; Macedo, Alexandre José; Gillet, Reynald (2022) [Journal article]Because of the ever-increasing multidrug resistance in microorganisms, it is crucial that we find and develop new antibiotics, especially molecules with different targets and mechanisms of action than those of the antibiotics ...