Browsing Pharmacy - Undergraduate degree by Subject "Biginelli reaction"
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In vitro antifungal activity of dihydropyrimidinones/thiones against Candida albicans and Cryptococcus neoformans
(2017) [Work completion of graduation]Since the Monastrol discovery in 1999 as the first inhibitor of Eg5, functionalized dihydropyrimidinones/thiones (DHPMs) have emerged as prototypes for drug design in different targets. The present work aimed to evaluate ... -
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
(2010) [Work completion of graduation]Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, ...