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dc.contributor.authorLima, Ana Flavia Barros da Silvapt_BR
dc.contributor.authorMiguel, Sandro René Pinto de Sousapt_BR
dc.contributor.authorCohen, Mírianpt_BR
dc.contributor.authorZimmermann, Jacques Josépt_BR
dc.contributor.authorShansis, Flavio Milmanpt_BR
dc.contributor.authorCruz, Luciane Nascimentopt_BR
dc.contributor.authorZiegelmann, Patricia Klarmannpt_BR
dc.contributor.authorPolanczyk, Carisi Annept_BR
dc.contributor.authorFleck, Marcelo Pio de Almeidapt_BR
dc.date.accessioned2018-09-05T02:28:59Zpt_BR
dc.date.issued2018pt_BR
dc.identifier.issn1516-4446pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/181635pt_BR
dc.description.abstractObjective: To assess the effectiveness of three mood disorder treatment algorithms in a sample of patients seeking care in the Brazilian public healthcare system. Methods: A randomized pragmatic trial was conducted with an algorithm developed for treating episodes of major depressive disorder (MDD), bipolar depressive episodes and mixed episodes of bipolar disorder (BD). Results: The sample consisted of 259 subjects diagnosed with BD or MDD (DSM-IV-TR). After the onset of symptoms, the first treatment occurred B6 years and the use of mood stabilizers began B12 years. All proposed algorithms were effective, with response rates around 80%. The majority of the subjects took 20 weeks to obtain a therapeutic response. Conclusions: The algorithms were effective with the medications available through the Brazilian Unified Health System. Because therapeutic response was achieved in most subjects by 20 weeks, a follow-up period longer than 12 weeks may be required to confirm adequate response to treatment. Remission of symptoms is still the main desired outcome. Subjects who achieved remission recovered more rapidly and remained more stable over time.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofRevista brasileira de psiquiatria (1999). São Paulo. Vol. 40, n. 1 (jan./mar. 2018), p. 26-34pt_BR
dc.rightsOpen Accessen
dc.subjectTranstornos do humorpt_BR
dc.subjectMood disordersen
dc.subjectBipolaren
dc.subjectTranstorno depressivo maiorpt_BR
dc.subjectMood disordersen
dc.subjectTranstorno bipolarpt_BR
dc.subjectUnipolaren
dc.subjectAgentes antipsicóticospt_BR
dc.subjectClinical drug studiesen
dc.subjectProgramas nacionais de saúdept_BR
dc.subjectEconomic issuesen
dc.subjectBrasilpt_BR
dc.subjectEpidemiologyen
dc.titleEffectiveness evaluation of mood disorder treatment algorithms in Brazilian public healthcare patientspt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001074218pt_BR
dc.type.originNacionalpt_BR


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