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dc.contributor.authorBlay, Sergio Luispt_BR
dc.contributor.authorAguiar, João Vicente Augustopt_BR
dc.contributor.authorPassos, Ives Cavalcantept_BR
dc.date.accessioned2017-01-05T02:30:31Zpt_BR
dc.date.issued2016pt_BR
dc.identifier.issn1178-2021pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/150444pt_BR
dc.description.abstractBackground: The association between depression, anxiety, and polycystic ovary syndrome (PCOS) is still unclear. Therefore, a systematic review and meta-analysis was conducted to assess the rates of comorbid psychiatric disorders among women with PCOS compared to women without it. Methods: PubMed/MEDLINE, Embase, PsycINFO, and Web of Science databases were searched from inception to November 27, 2015. Studies were eligible for inclusion if they were original reports in which the rates of mood (bipolar disorder, dysthymia, or major depressive disorder), obsessive–compulsive spectrum disorders, trauma- and stressor-related disorders, anxiety disorders or psychotic disorders, somatic symptom and related disorders, or eating disorders had been investigated among women with an established diagnosis of PCOS and compared with women without PCOS. Psychiatric diagnosis should have been established by means of a structured diagnostic interview or through a validated screening tool. Data were extracted and pooled using random effects models. Results: Six studies were included in the meta-analysis; of these, five reported the rates of anxiety and six provided data on the rates of depression. The rate of subjects with anxiety symptoms was higher in patients with PCOS compared to women without PCOS (odds ratio (OR) =2.76; 95% confidence interval (CI) 1.26 to 6.02; Log OR =1.013; P=0.011). The rate of subjects with depressive symptoms was higher in patients with PCOS compared to women without PCOS (OR =3.51; 95% CI 1.97 to 6.24; Log OR =1.255; P,0.001). Conclusion: Anxiety and depression symptoms are more prevalent in patients with PCOS.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofNeuropsychiatric disease and treatment. Auckland. Vol. 12 (Nov. 2016), p. 2895-2903.pt_BR
dc.rightsOpen Accessen
dc.subjectSíndrome do ovário policísticopt_BR
dc.subjectPolycystic ovary syndromeen
dc.subjectDepressionen
dc.subjectTranstornos mentaispt_BR
dc.subjectAnxietyen
dc.subjectMetanálisept_BR
dc.subjectEpidemiological surveyen
dc.subjectMeta-analysisen
dc.subjectSystematic reviewen
dc.titlePolycystic ovary syndrome and mental disorders : a systematic review and exploratory meta-analysispt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001008644pt_BR
dc.type.originEstrangeiropt_BR


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