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dc.contributor.advisorSchapoval, Elfrides Eva Schermanpt_BR
dc.contributor.authorBattisti, Fernandapt_BR
dc.date.accessioned2016-07-12T02:15:49Zpt_BR
dc.date.issued2012pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/143468pt_BR
dc.description.abstractEquinocandins is a new class of antifungic used for systemic infection. The anidulafungin is a new equinocandin that has fungicide activity against Candida spp. and fungistatic activity against Aspergillus spp. There is not microbiological assay about the potency of anidulafungin in papers. The aim of this study is develop and validate a microbiological assay to determine the potency of anidulafungin. The parametres analyzed during the validation was linearity (r=0.992), precision (DPR < 5%), accuracy (99.4%) and specificity. The results show that the method is suitable to quality control.en
dc.format.mimetypeapplication/pdf
dc.language.isoporpt_BR
dc.rightsOpen Accessen
dc.subjectAnidulafunginen
dc.subjectValidação : Métodos de análise de fármacospt_BR
dc.subjectCandida albicansen
dc.subjectAnidulafunginapt_BR
dc.subjectMicrobiological assayen
dc.subjectAntifúngicospt_BR
dc.titleDesenvolvimento e validação de método microbiológico de difusão em ágar - cilindros em placas para doseamento de anidulafunginapt_BR
dc.typeTrabalho de conclusão de graduaçãopt_BR
dc.contributor.advisor-coMiron, Diogo dos Santospt_BR
dc.identifier.nrb000898111pt_BR
dc.degree.grantorUniversidade Federal do Rio Grande do Sulpt_BR
dc.degree.departmentFaculdade de Farmáciapt_BR
dc.degree.localPorto Alegre, BR-RSpt_BR
dc.degree.date2012pt_BR
dc.degree.graduationFarmáciapt_BR
dc.degree.levelgraduaçãopt_BR


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