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dc.contributor.authorGarcia, Angelinapt_BR
dc.contributor.authorDermarchi, Dario A.pt_BR
dc.contributor.authorRodrigues, Luciana Tovopt_BR
dc.contributor.authorPauro, Maiapt_BR
dc.contributor.authorCallegari-Jacques, Sidia Mariapt_BR
dc.contributor.authorSalzano, Francisco Mauropt_BR
dc.contributor.authorHutz, Mara Helenapt_BR
dc.date.accessioned2015-11-10T02:41:04Zpt_BR
dc.date.issued2015pt_BR
dc.identifier.issn1415-4757pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/129410pt_BR
dc.description.abstractThe population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofGenetics and molecular biology. Ribeirão Preto, SP. Vol. 38, no. 3, (2015), p. 324-331pt_BR
dc.rightsOpen Accessen
dc.subjectAIMsen
dc.subjectMarcadores genéticospt_BR
dc.subjectCórdobaen
dc.subjectAncestralidadept_BR
dc.subjectArgentinapt_BR
dc.subjectSan Luisen
dc.subjectMigrationen
dc.subjectPopulation structureen
dc.titleHigh interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)pt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000974458pt_BR
dc.type.originNacionalpt_BR


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