Aspectos regio- e estereoquímicos da adição de michael assimétrica via iminas quirais com centros estereogênicos pré-existentes
Fecha
2003Autor
Otro título
Regio- and stereochemical aspects of the asymmetric michael addition using chiral imines bearing a resident stereogenic center
Materia
Abstract
The asymmetric Michael addition reactions using chiral imines, under neutral conditions (deracemizing alkylation process), constitute one of the main methods for the stereocontrolled elaboration of quaternary carbon centers. This protocol is based on the conjugate addition of secondary chiral enamines to electron-deficient alkenes. The focus of this report deals with the discussion of regio- and stereochemical aspects of the deracemizing alkylation process concerning enamines bearing a resident ...
The asymmetric Michael addition reactions using chiral imines, under neutral conditions (deracemizing alkylation process), constitute one of the main methods for the stereocontrolled elaboration of quaternary carbon centers. This protocol is based on the conjugate addition of secondary chiral enamines to electron-deficient alkenes. The focus of this report deals with the discussion of regio- and stereochemical aspects of the deracemizing alkylation process concerning enamines bearing a resident chiral center. ...
En
Química nova. São Paulo. Vol. 26, n. 5 (2003), p. 717-725
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Artículos de Periódicos (39074)Ciencias Exactas y Naturales (5943)
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