Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil
dc.contributor.author | Santos, Helena Barreto dos | pt_BR |
dc.contributor.author | Machado, Denise Pires | pt_BR |
dc.contributor.author | Camey, Suzi Alves | pt_BR |
dc.contributor.author | Kuchenbecker, Ricardo de Souza | pt_BR |
dc.contributor.author | Barth, Afonso Luis | pt_BR |
dc.contributor.author | Wagner, Mario Bernardes | pt_BR |
dc.date.accessioned | 2011-07-27T06:00:48Z | pt_BR |
dc.date.issued | 2010 | pt_BR |
dc.identifier.issn | 1471-2334 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/30378 | pt_BR |
dc.description.abstract | Background: There are few studies in Brazil that address baseline prevalence of MRSA colonization and associated risk factors at hospital admission, or the incidence of nosocomial colonization. We report a prospective study in a tertiary-care, university-affiliated hospital to implement a new MRSA control policy at the institution. Methods: A cohort of randomly selected patients admitted to emergency and clinical wards at our hospital was followed until discharge. Nasal swabs were taken for identification of MRSA-colonized patients and detection of SCCmecA in positive cultures, at admission and weekly thereafter. Multivariate analysis using a log-binomial analysis was used to identify risk factors for colonization. Results: After screening 297 adult patients and 176 pediatric patients, the prevalence of MRSA at admission was 6.1% (95%CI, 3.6% to 9.4%), in the adult population and 2.3% (95%CI, 0.6% to 5.7%), for children. From multivariate analysis, the risk factors associated with colonization in adults were: age above 60 years (P = 0.019) and hospitalization in the previous year (P = 0.022). Incidence analysis was performed in 276 MRSA-negative patients (175 adults and 101 children). Acquisition rate was 5.5/1,000 patient-days for adults (95%CI, 3.4 to 8.5/1,000 patients-days), and 1.1/1,000 patient-days for children (95%CI, 0.1 to 4.0/1,000 patients-days). Conclusions: The identification of MRSA carriers is a step towards establishing a control policy for MRSA, and helps to identify measures needed to reduce colonization pressure and to decrease the high acquisition rate in hospitalized patients. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | BMC infectious diseases. London. Vol. 10 (14 nov. 2010), p. 328 (7 p.) | pt_BR |
dc.rights | Open Access | en |
dc.subject | Epidemiologia | pt_BR |
dc.subject | Infecção hospitalar | pt_BR |
dc.subject | Hospitais universitários | pt_BR |
dc.subject | Estatística e dados numéricos | pt_BR |
dc.subject | Incidência | pt_BR |
dc.subject | Staphylococcus aureus resistente à meticilina | pt_BR |
dc.subject | Prevalência | pt_BR |
dc.subject | Estudos prospectivos | pt_BR |
dc.subject | Fatores de risco | pt_BR |
dc.subject | Infecções estafilocócicas | pt_BR |
dc.subject | Brasil | pt_BR |
dc.title | Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 000777002 | pt_BR |
dc.type.origin | Estrangeiro | pt_BR |
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