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dc.contributor.authorPfeifer, Lucinéia Orsolinpt_BR
dc.contributor.authorNardi, Angélica Trevisan dept_BR
dc.contributor.authorSilva, Larissa Xavier Neves dapt_BR
dc.contributor.authorBotton, Cíntia Ehlerspt_BR
dc.contributor.authorNascimento, Daniela Meirelles dopt_BR
dc.contributor.authorTeodoro, Juliana Lopespt_BR
dc.contributor.authorSchaan, Beatriz D'Agordpt_BR
dc.contributor.authorMoraes, Daniel Umpierre dept_BR
dc.date.accessioned2023-04-19T03:24:52Zpt_BR
dc.date.issued2022pt_BR
dc.identifier.issn2198-9761pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/257187pt_BR
dc.description.abstractBackground: The prevalence of type 2 diabetes mellitus increases with age, and people with type 2 diabetes are more affected by reductions in functional performance. Although exercise interventions are recommended for people with diabetes, it is relevant to assess the effects of different training modes on the available functional outcomes. Therefore, our purpose was to systematically assess the effect of different physical exercise modalities in patients with type 2 diabetes with an average age of 45 years or older on outcomes used to measure functional capacity. Methods: A systematic review and meta-analysis of controlled trials was conducted. Seven databases were searched from January 1987 to December 2021 (PubMed, Physiotherapy Evidence Database, Cochrane Library, SPORTDiscus, and in grey literature: Open Grey and Google Scholar). Eligible studies should last 8 weeks or longer, comparing structured exercise training and non-exercise control for one out of six pre-specified functional capacity outcomes (Timed Up and Go test, chair stands, walking performance, upper-limb muscle strength, lower-limb muscle strength, physical fitness parameter), in patients with type 2 diabetes, aged ≥ 45 years. The risk of bias was assessed with the Downs & Black checklist. Pooled mean differences were calculated using a random-effects model, followed by sensitivity and meta-regression analyses. Results: Of 18,112 references retrieved, 29 trials (1557 patients) were included. Among these, 13 studies used aerobic training, 6 studies used combined training, 4 studies used resistance training, 3 studies had multiple intervention arms and 3 studies used other types of training. Exercise training was associated with an increase in functional capacity outcomes, as reflected by changes in 6-min walk test (n = 8) [51.6 m; 95% CI 7.6% to 95.6%; I2 92%], one-repetition maximum leg-press (n = 3) [18.0 kg; 95% CI 4.0% to 31.9%; I2 0%], and maximum oxygen consumption (VO2max) (n = 20) [2.41 mL/kg·min; 95% CI 1.89% to 2.92%; I2 100%] compared with control groups. In sensitivity and subgroup analyses using VO2max as outcome and stratified by type of study (randomized and non-randomized controlled clinical trials), duration of diabetes diagnosis, and sex, we observed overlapping confidence intervals. Meta-regression showed no association between glycated hemoglobin (HbA1C) levels and VO2max [p = 0.34; I2 99.6%; R2 = 2.6%]. In addition, the quality of the included studies was mostly low. Conclusion: The results indicate that structured physical exercise programs might improve functional capacity in patients with type 2 diabetes, except for the upper-limb muscle strength. However, we could not identify potential effect predictors associated with directional summary estimates.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofSports Medicine - Open. [S.l.]: SpringerOpen, 2015-. Vol. 8 (2022), 34, 22 p.pt_BR
dc.rightsOpen Accessen
dc.subjectExercício físicopt_BR
dc.subjectFunctional capacityen
dc.subjectStructured exercise trainingen
dc.subjectDiabetes mellitus tipo 2pt_BR
dc.subjectType 2 diabetesen
dc.subjectRevisão sistemáticapt_BR
dc.subjectSystematic reviewen
dc.subjectDesempenho físico funcionalpt_BR
dc.subjectMetanálisept_BR
dc.subjectMeta-analysisen
dc.titleAssociation between physical exercise interventions participation and functional capacity in individuals with type 2 diabetes : a systematic review and meta-analysis of controlled trialspt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb001163538pt_BR
dc.type.originEstrangeiropt_BR


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